Katalina Mörmann’s Post

From the basics of cell culture to advanced 3D models and therapeutic applications, the quality and consistency of media and reagents are key! High-quality components ensure reliable and reproducible results, vital for research and clinical progress. By using specialized growth factors, cytokines, and cutting-edge live-cell analysis technologies like the Incucyte® system, researchers can optimize cell culture conditions, enhance data accuracy, and drive innovative treatments forward. Our latest eBook highlights the importance of meticulous cell culture practices, showing how superior media and technologies can lead to groundbreaking advancements in research and therapy. 📚✨ Download now: https://ow.ly/LvUl50Tv7i2 #CellCulture #CellAnalyis #3DCellCulture #Organoids #Spheroids #Biotechnology

🔍Very interesting article in the September edition of GEN (Genetic Engineering & Biotechnology News, pages 22-24) comparing scale-out vs. scale-up: https://lnkd.in/eEUUQkHD For RNA production, scaling out provides key advantages: 🤸♂️ Flexibility in production scale ✨ Ease of operation 💰 CAPEX savings 🚀 Improved production performance   At Quantoom Biosciences, our RNA production operates in a repeat batch mode: 20mL IVT. All IVT reactions in Ntensify™ midi perform uniformly and with minimized shear forces. Plus, purchasing disposables in bulk helps reduce costs, as they are suitable across all production scales. By choosing scale-out, RNA production is efficient, adaptable, and cost-effective! #RNA #ScaleOut #Ntensify

Save big on bioscience research essentials! 🔬 Dive into our 50% OFF sale on Protease Inhibitor Cocktail for Mammalian Cells and Tissue (PIC-2, A-0014). Don’t miss out! PIC-2 is a mixture of protease inhibitors that will inhibit many proteases including aspartic, cysteine, serine, metalloproteases, and aminopeptidases. To learn more or order online, go to: https://lnkd.in/gzv7GKXr Email or call us if you have any questions or want to place an order! #ResearchEssentials #ProteaseInhibitor #ProteaseInhibitorCocktail #LabLife #Sale #Biosciences #LifeSciences #Research

Unlock the power of Targeted Lipidomics with our state-of-the-art services! 🧬 Using high-res mass spectrometry & isotope-labeled standards, we provide absolute quantification, fulfilling all detection & validation needs. 🌟 High throughput, wide applicability, & exceptional sensitivity. #Lipidomics #HighResolution #MassSpectrometry #Biotech #ScienceInnovation https://lnkd.in/g29DiPT6

🔬 Rely On Our 20+ Years Of #LCMS Expertise For Your #Oligonucleotides—ASOs, SiRNAs, Aptamers, MiRNA, And Beyond. We’re Trusted Partners Of #Biotech, Pioneering Treatments For The #Undruggable.🧬 🚀 Swift LC-MS Method Development For #DrugDiscovery To #GLP Studies 🔍 Unmatched #Selectivity, With Low LLOQ In Tissues And Fluids 📈 Advanced Sample Prep For High #Specificity And #ExtractionRecovery 🎯 Consistent Assay Reproducibility For #PK And #Biodistribution Data 👨🔬 Trust Our Mass Spec And Hybrid ELISA Experts To Propel Your Oligonucleotide Methods. Speak To Our Scientists And Explore Case Studies Demonstrating Our Hand-On Experience With Oligos. https://lnkd.in/dw2ra3KM

Revolutionizing Nucleic Acid Extraction: Introducing Ionic by Bionano We're excited to offer the Ionic system - a game-changer in automated DNA and RNA isolation, especially for FFPE samples. Superior Automated Approach: 🔹 Minimizes hands-on time to just 3 minutes per sample 🔹 Reduces errors and simplifies workflow 🔹 Eliminates separate paraffin removal for FFPE samples Higher Yields and Quality: 🔹 Up to 4.5x more nucleic acid extracted 🔹 Reduced fragmentation due to gentle processing 🔹 No sample loss from binding or stripping Innovative Technology: 🔹 Utilizes Isotachophoresis (ITP) for superior separation 🔹 No organic solvents, harsh buffers, or repetitive washing 🔹 Integrated sensor for precise extraction Versatile Applications: 🔹 Ideal for oncology research with FFPE tissues 🔹 Suitable for various biological samples Interested in elevating your nucleic acid purification process? Contact our team at Bucher Biotec AG to learn how Ionic can transform your research. #NucleicAcidExtraction #BiotechInnovation #LifeSciences #BucherBiotec

Beyond Viability: Advancing CHO Cell Culture Process Strategies to Modulate Host Cell Protein Levels While purification strategies usually offer substantial HCP clearance, certain problematic HCPs, particularly lipases, pose significant challenges. This study investigates the accumulation of various problematic HCPs in CHO cell culture using transcriptomics, revealing correlations between cell culture parameters and HCP activity. Contrary to conventional assumptions, viability alone does not reliably predict HCP levels, with factors such as clone selection, host cell line choice, and media feed type significantly influencing HCP accumulation. Leveraging transcriptomics-based approaches, we demonstrate the potential of upstream process control strategies to mitigate HCP presence and improve biologic product quality. Our findings underscore the importance of considering diverse cell culture parameters in bioprocess optimization to ensure product stability and quality. https://lnkd.in/g27Z3pc3 #aspenalert #biotech #bioprocess

The Dr. Oligo 768XLc has the highest throughput among all Dr. Oligo synthesizers, making it ideal for production facilities and large research labs aiming to produce large amounts of oligos per run! Feature Highlights: Throughput: Ultra-High Throughput Synthesize: DNA, RNA, LNA, 2'-Modified RNA, Mixed Backbones DNA and RNA, and more Oligos Per Run: 1-768 Synthesis Scale: 2 nmol to 100 nmol Dimensions: 62.68in x 19in x 31.67in Max Reagents: 25 with 15 special reagents Qualification Services: IQ, OQ, PM Modern Software: Hardware Mapping, Protocol Editor, Ox and Cap Configuration, Full Manual Mode, Security & Encryption, Software Updates, and More Learn More about the Dr. Oligo 768XLc:  https://lnkd.in/gd8UHcdJ #DrOligo768XLc #OligoSynthesis #Biotech #LabEquipment #MolecularBiology #ResearchInnovation #Science #Biotechnology #Genomics #Pharmaceuticals #dnasynthesis #rnasynthesis #oligosynthesis #droligo #biolytic #oligosynthesizer 

Minimizing endotoxin level is critical for cell culture and bioprocessing applications. Why is it important to ensure low endotoxin levels in your formulation or cell culture? Endotoxins, also known as lipopolysaccharides, are toxic pyrogens found in the outer membrane of Gram-negative bacteria and are released into their environment following the lysis of their host cells. These microbes can influence results when exposed to scientific experiments, often leading to discrepancies in molecular biology, assay development, and purification processes. At Boston BioProducts, we offer full customization of your buffers and reagents, including a range of quality control tests such as endotoxin testing. Learn more: https://hubs.la/Q02HFVlp0 #endotoxin #pyrogen #bacteria #gramnegative #LALAssay #microbes #labsafety

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