ASP.NET MVC 4 includes updates like HTML 5 support, mobile project templates, and jQuery Mobile support. The document discusses the basics of the MVC pattern and how it differs from ASP.NET Web Forms by separating domain logic from the user interface. It provides examples of how MVC isolates the model, view, and controller portions of an application. The document also emphasizes techniques like test-driven development, dependency injection, and separation of concerns that make applications built with MVC more modular and maintainable.