This document discusses using ProxySQL and Percona XtraDB Cluster (PXC) together to provide transparent high availability and scalability for applications. It provides an overview of PXC and how it addresses issues with traditional MySQL replication. It also describes features of ProxySQL like query caching, routing, and firewall capabilities. Finally, it provides an example configuration of ProxySQL and PXC together with host groups, servers, users, and rules to balance loads and ensure data integrity.