This document proposes and evaluates approximate hybrid high radix encoding techniques for designing energy-efficient inexact multipliers. A novel approximate hybrid high radix encoding is proposed that encodes the most significant bits of the multiplicand using radix-4 encoding and the least significant bits using approximate radix-2k encoding. Approximations are performed by rounding high radix values to the nearest power of two. The technique is applied to design 16x16 bit multipliers using 4:2 compressors to reduce the area compared to normal adders. Simulation results show the proposed design achieves area savings compared to an accurate radix-4 multiplier. The document also explores applying the proposed encoding technique to the design of finite impulse response filters using