Each month 12 million people use Elsevier’s ScienceDirect platform. The Mendeley social network has 4.6 million registered users. 3500 institutions make use of ClinicalKey to bring the latest in medical research to doctors and nurses. How can we help these users be more effective? In this talk, I give an overview of how Elsevier is employing data science to improve its services from recommendation systems, to natural language processing and analytics. While data science is changing how Elsevier serves researchers, it’s also changing research practice itself. In that context, I discuss the impact that large amounts of open research data are having and the challenges researchers face in making use of it, in particular, in terms of data integration and reuse. We are at just beginning to see of how technology and data is changing science correspondingly this impacts how best to empower those who practice it.