In this article, 180 gastric images taken with Light Microscope help are used. Maximally Stable
Extremal Regions (MSER) features of the images for classification has been calculated. These MSER features
have been applied Discrete Fourier Transform (DFT) method. High-dimensional of these MSER-DFT feature
vectors is reduced to lower-dimensional with Local Tangent Space Alignment (LTSA) and Neighborhood
Preserving Embedding (NPE). When size reduction process was done, properties in 5, 10, 15, 20, 25, 30, 35, 40,
45, and 50 dimensions have been obtained. These low-dimensional data are classified by Random Forest (RF)
classification. Thus, MSER_DFT_LTSA-NPE_RF method for gastric histopathological images have been
developed. Classification results obtained with these methods have been compared. According to the other
methods, classification results for gastric histopathological images have been found to be higher.