The document discusses how to use Calico to secure the network interfaces of a host, called "host endpoints", in addition to workload endpoints like containers and VMs. Calico supports the same security policy model for host endpoints as it does for workloads. It distinguishes host and workload interfaces by configurable prefix. The steps to enable host endpoint security include installing Calico's Felix daemon, initializing the etcd database, adding basic connectivity policy, and creating host endpoint objects for each interface in etcd.