Outread’s Post

This is an awesome accessible reference library on human light interaction (HLI) beyond circadian rhythms! As more data amasses, I look forward to the day when we put as much attention, interest and capital into understanding our light diet as we do our food diet. The data here covers eye health, tissue damage/stress, short&long wavelength interactions, protective wavelengths, vision performance, systemic effects, and skin. If the critical role of your light environment on your health is not yet on your radar, please take a look - once you see, you can't unsee.

☀️ 𝗔𝗻𝗻𝗼𝘂𝗻𝗰𝗲𝗺𝗲𝗻𝘁 ☀️ We are pleased to introduce our new collection of light physiology literature on Pixun's website. This resource features concise bullet-point summaries, complete with citations and links, covering topics such as: • 𝗠𝘆𝗼𝗽𝗶𝗮 𝗮𝗻𝗱 𝗟𝗶𝗴𝗵𝘁 𝗘𝘅𝗽𝗼𝘀𝘂𝗿𝗲 • 𝗕𝗹𝘂𝗲 𝗟𝗶𝗴𝗵𝘁 𝗮𝗻𝗱 𝗧𝗶𝘀𝘀𝘂𝗲 𝗦𝘁𝗿𝗲𝘀𝘀 • 𝗜𝗻𝘁𝗲𝗿𝗮𝗰𝘁𝗶𝗼𝗻𝘀 𝗕𝗲𝘁𝘄𝗲𝗲𝗻 𝗦𝗵𝗼𝗿𝘁 𝗮𝗻𝗱 𝗟𝗼𝗻𝗴 𝗪𝗮𝘃𝗲𝗹𝗲𝗻𝗴𝘁𝗵𝘀 • 𝗣𝗿𝗼𝘁𝗲𝗰𝘁𝗶𝘃𝗲 𝗘𝗳𝗳𝗲𝗰𝘁𝘀 𝗼𝗳 𝗥𝗲𝗱 𝗮𝗻𝗱 𝗡𝗲𝗮𝗿-𝗜𝗻𝗳𝗿𝗮𝗿𝗲𝗱 𝗟𝗶𝗴𝗵𝘁 • 𝗟𝗶𝗴𝗵𝘁 𝗦𝗲𝗻𝘀𝗶𝘁𝗶𝘃𝗶𝘁𝘆 • 𝗙𝗹𝗶𝗰𝗸𝗲𝗿 • 𝗦𝘆𝘀𝘁𝗲𝗺𝗶𝗰 𝗛𝗲𝗮𝗹𝘁𝗵 𝗘𝗳𝗳𝗲𝗰𝘁𝘀 • 𝗦𝗸𝗶𝗻 𝗘𝗳𝗳𝗲𝗰𝘁𝘀 Explore our latest insights and deepen your understanding of how light impacts health. Visit our website to learn more! https://lnkd.in/enPPArfD

How do cellular powerhouses, the mitochondria, evolve as we age? A study published in Advanced Biology, led by Antentor "A.J." Hinton, Jr., Ph.D., Vanderbilt University reveals the changes within these vital organelles, shedding light on their impact on our metabolic health. Key highlights: 1️⃣ Changes in Cristae and Mitochondrial Structure: While overall mitochondrial size increases with age, the study found a significant decrease in the surface area, volume, and complexity of cristae. This structural transformation directly affects the efficiency of mitochondrial function, potentially impacting our overall energy levels and health. 2️⃣ Influence on Thermogenic Capacity: The shape of mitochondria was found to play a strategic role in determining our body's ability to generate heat and burn fat. Spherical mitochondria exhibited higher thermogenic function, while elongated ones, more prevalent in older individuals, showed reduced capacity. By studying mitochondrial structure across different tissues and species, the team hopes to gain a deeper understanding of aging mechanisms and identify potential therapeutic targets for treating age-related ailments and mitochondrial dysfunctions. 🔗 Read more: https://lnkd.in/duP_P_pi. Stay tuned for #TargetingMitochondria2024 this October for more updates mitochondria research and aging. #WorldMitochondriaSociety #TargetingMitochondria #mitochondria #mitochondriaresearch #aging

The enteric nervous system (ENS) is a #nerve network composed of neurons and glial cells that regulates the motor and secretory functions of the #gastrointestinal (GI) tract. In this paper, the authors aimed to highlight the role of the ENS in Parkinson’s disease pathogenesis based on evidence observed in animal models and using a translational perspective. 📝 Beyond the Microbiota: Understanding the Role of the Enteric Nervous System in Parkinson’s Disease from Mice to Human — Montanari, et al. Full text is available 👇 https://lnkd.in/dhpdgEsZ #medicine #health #research #science

According to a study headed by Leiden University biologist Meiru Wang, nanoplastics can build up in the hearts of growing chicken embryos. Researchers noticed that after injecting fluorescently marked polystyrene nanoparticles into the embryos' bloodstream, the particles penetrated blood vessel walls and greatly aggregated in the kidneys, liver, and heart. Interestingly, nanoplastics were also found in avascular heart cushions, which are cardiac tissues devoid of blood vessels. This suggests that the nanoplastics entered the developing heart tissue through tiny holes. Given that previous studies have connected nanoparticles to an increased risk of heart attacks and strokes, these findings raise concerns about possible health implications. Nanoplastics, would be a big threat to the health and metabolism of each and every organism.

💡- Unlocking the Secrets of Regeneration with Zebrafish Did you know zebrafish can regenerate their hearts, brains, and fins? These remarkable creatures are revolutionizing medical research. By studying their regenerative abilities, scientists aim to develop treatments for heart disease, neurological disorders, and more. Zebrafish are not just model organisms; they are key to unlocking the future of regenerative medicine. 🐟🔬 #RegenerativeMedicine #ScientificResearch #Biotechnology

As a microbiologist, I am constantly amazed by the complexity of the microbial world and its impact on human health. However, the idea of a brain microbiome—microbes or their components residing in the brain—is truly astonishing. Recent research reveals potential links between these brain-associated microbes and neurological functions, including neuroinflammation, neurotransmitter regulation, and even diseases like Alzheimer’s and Parkinson’s. This challenges our understanding of the brain as a sterile organ and opens exciting questions about how microbes influence our most vital organ. From a microbiological standpoint, understanding how microbes breach the blood-brain barrier and interact with neural tissue could revolutionize treatments for neurodegenerative conditions. If you are interested you can read the article posted on Frontiers following this link: https://lnkd.in/dSNpVwgN

Are you intrigued by the idea of living a longer, healthier life? Recent scientific advancements suggest that this dream might be closer to reality than we think. The Interventions Testing Program (ITP), a highly regarded initiative under the US National Institute on Aging, is leading the charge by testing compounds that could potentially extend lifespan in mice. Here's what you need to know: Genetic Diversity Matters: The ITP uses genetically diverse mice (UM-HET3) to ensure results are more representative of a normal population, unlike studies using highly inbred mice which often don't translate well to humans. Rigorous Testing: By conducting experiments across three different labs and using large sample sizes, the ITP ensures that their findings on lifespan extension are robust and reproducible. Promising Results: Several compounds have shown potential in extending the lifespan of mice, including rapamycin, acarbose, and 17α-estradiol, each with unique mechanisms and effects. Continued Research: While these findings are promising, translating them to human longevity is complex and requires further research. However, the ITP's work provides a hopeful glimpse into a future where aging might be more within our control. Remember, while the science of lifespan extension is fascinating and full of potential, it's important to approach it with a critical mind and understand that these studies are preliminary. The journey to human application is long and requires rigorous testing and validation. Stay tuned to the latest in longevity science and imagine a future where we all live healthier, longer lives. Let's embrace the possibilities responsibly! Remember, while the science is promising, it's important to approach these findings with a nuanced understanding and look forward to more research in this exciting field. Stay curious and informed! 🔗 Read the full article here: https://lnkd.in/eb5ahSck #LongevityScience #LifespanExtension #HealthInnovation #AgingResearch #ScientificBreakthroughs #FutureOfHealth #HealthyAging #ScienceMatters #InnovativeResearch #StayInformed

🧬 Exciting New Breakthrough in Longevity Research! 🌱 Researchers have discovered a protein, OSER1, that could hold the key to why some individuals live longer than others. 🧑🔬 Found in both humans and animals, OSER1 is part of a group of proteins linked to ageing and lifespan. What's fascinating is that it's regulated by FOXO, a well-known longevity factor. This discovery could pave the way for future treatments aimed at extending life or preventing age-related diseases! As we continue to unlock the secrets of ageing, the potential for healthier, longer lives looks promising 🌟 #Longevity #AgingResearch #HealthInnovation #FutureOfMedicine #HealthyAging

Brain’s Waste Clearance Channels Mapped, Glymphatic Flows Confirmed https://lnkd.in/gFRFGTeM Scientists have long wondered about the network of pathways in the brain that is believed to clear metabolic wastes. Wastes include proteins such as amyloid and tau, which have been shown to form clumps and tangles in brain images of patients with Alzheimer’s disease. More than a decade ago, scientists at the University of Rochester first proposed the existence of a network of waste-clearance pathways in the brain akin to the body’s lymphatic system, part of the immune system. Those researchers confirmed it with real-time imaging of the brains of living mice. Due to its dependence on glial cells in the brain, they coined the term “glymphatic system” to describe it. Now, a new study by the Oregon Health & Science University (OHSU) reveals this network in people. The findings are published in the Proceedings of the National Academy of Sciences  in an article titled, “The perivascular space is a… Click here to view original post Click Here to Publish/Feature Your Company or Product News with Biotech Networks