Sano Genetics

Gene therapy and precision medicine hold incredible promise for people with genetic hearing loss, but the path to widespread adoption is filled with challenges. From the complexity of diagnosis to the high costs of development, accessibility, and ethical considerations, significant barriers remain. 🚧 In our latest blog post, we explore these challenges and discuss potential solutions to make precision medicine for hearing loss more effective, accessible, and equitable. Learn more👇 https://lnkd.in/ef2WiK4k #GeneTherapy #HearingLoss #PrecisionMedicine #Genomics #Healthcare

When Sharon Terry’s children were diagnosed with a rare genetic disorder, she didn’t wait for answers—she went out and found them. From learning genetics from scratch to co-discovering the PXE gene, building the first patient-led biobank, and helping pass the Genetic Information Nondiscrimination Act (GINA), Sharon’s journey is one of resilience, innovation, and advocacy. In a recent episode of The Genetics Podcast, we chat with Sharon to explore: 🔬 How patient-led research is changing biobanking and drug development ⚖️ The challenges of balancing industry partnerships with patient rights 🌍 Why global initiatives like IHOPE Genetic Health are crucial for underserved communities 📜 Whether GINA still protects patients in today’s world of widespread genetic testing A summary and the full episode are available on-demand now👇 https://lnkd.in/ekpSgDtw #Genetics #RareDisease #PatientAdvocacy #PrecisionMedicine

I had the pleasure of speaking with Rory Cellan-Jones after an introduction from a colleague, and the conversation turned into a beautifully written post on Rory's newsletter, "Always On" focussed on technology and health. I offered my perspective on genetic testing in Parkinson's Disease, and also how my own family experience with genetic testing in kidney disease has shaped my worldview. Anyone interested in technology, health, or Parkinson's Disease i'd highly encourage you to check it out and subscribe! https://lnkd.in/dsVS26d8

Wrapping up a few days of in-person team meetings with the leadership and extended-leadership teams from Sano Genetics. I love the flexibility of remote work, but also value the time together so much. Between meetings and dinner we squeezed in some time to visit the TWIST (The Way I See iT) Museum. It was an hour well spent to remind us all that solving big problems is challenging, but we are fortunate to work with a group that is smart and creative enough to take on the big challenges and to remember that no issue is as black and white as it seems at first glance. Thanks to the team for adding some color into my week and to Mina Frost for planning a delightful evening! Next stops in Q2 include: ⚫ World Orphan Drug Congress (Boston April 22-24) ⚫ Global Clinical Supply Group (San Antonio April 28-30) ⚫ PPALS (Sioux Falls May 5-9) ⚫ Day trips for meetings in Philadelphia and NYC If you will be at any of those events and would like to meet, send me a note!

🎙️Episode 181 of #TheGeneticsPodcast is live! 🚀 This week, Patrick is joined by Salvador Rico, Chief Medical Officer at Encoded Therapeutics Inc. Tune in as they discuss: 🔬 The tough lessons and incredible recoveries Salvador witnessed in a gene therapy trial for X-linked myotubular myopathy (XLMTM) 🧬 The frustrations and rewards of working in genetics 🩺 The pivotal moments that led Salvador to precision medicine drug development Listen by following the link below 👇 or simply search “The Genetics Podcast” on your go-to podcast platform. 🎧 https://pod.fo/e/2c22b3 📽️ https://lnkd.in/gPCkMk96

Looking forward to seeing colleagues and friends at the American Academy of Neurology (AAN) Conference next week. I'll be attending with Benjamin Jackson on behalf of Sano Genetics so please let me know if you have time to connect during the conference. #neurology #clinicaltrials #precisionmedicine #biotech #pharma #biopharma #healthcaretechnology #clinicalresearch

Hearing loss is the most common sensory condition in the world, yet for many, treatment options remain limited. While advances in precision medicine such as gene therapy and precision medicine offer hope, barriers such as cost, accessibility, and ethical concerns must be addressed. 💰The cost of developing a gene therapy can exceed $1.9 billion 👂50%+ of severe genetic hearing loss cases are linked to just two genes, yet therapies remain elusive ⚖️Equitable access is a major challenge, with many affected communities underserved At the same time, Deaf culture plays an essential role in the discussion around genetic hearing loss treatment. How do we balance medical advancements with respect for identity and inclusivity? Read more👇 https://lnkd.in/euJGjsUt #GeneTherapy #HearingLoss #PrecisionMedicine #Genomics #Healthcare

Did you know that in addition to making progress for the 20% of the world's population impacted by hearing loss, investing in ear and hearing care services yields a return of $16 for every dollar spent? That's why our latest whitepaper focuses in on this topic, covering key ares such as: 💡 Genetic foundations: Dive deep into the genetic causes of hearing loss. 💉 Gene therapy: Discover recent advances in gene therapy that are setting new treatment standards. 💰Economic Benefits: Understand the broader economic impact of effective hearing loss treatment. Empower your innovation in this space with key insights: https://lnkd.in/eujy-icn #PrecisionMedicine #Genetics #HearingLoss

What if the next breakthrough drug target isn’t in the known proteome—but in the thousands of hidden proteins we’ve yet to study? 🔬 That’s the question driving ProFound Therapeutics, a company uncovering an entirely new layer of biology: the expanded human proteome. Using advanced ribosome profiling (Ribo-Seq), they are identifying previously unknown proteins that could hold the key to new treatments for cancer, metabolic disease, and more. We talked to CEO Dr. John Lepore about why and how this might be the future of drug discovery on a recent episode of The Genetics Podcast. Read a summary or listen in full 👇 https://lnkd.in/eKbJ_rrY #Genomics #Proteomics #DrugDiscovery #Biotech #PrecisionMedicine

Recent advances in gene therapy and precision medicine are changing the way we understand and treat genetic hearing loss. 👂 With next-generation sequencing (NGS), doctors can now pinpoint genetic causes earlier than ever, and new gene therapy trials are showing that, for some patients, restoring hearing is becoming a real possibility. However, key barriers remain: 💰 High costs of development and treatment 🌍 Limited accessibility in low- and middle-income countries ⚖️ Ethical concerns around genetic interventions Our latest whitepaper dives into the current landscape, challenges, and the future of genetic hearing loss treatment. Find out more 👇 https://lnkd.in/e9XZadEa #GeneTherapy #HearingHealth #Genomics #Biotech #PrecisionMedicine