BioMed X Institute

What can early metazoans teach us about the origins of cell type diversity? We are pleased to announce the next session of our Lunch Talk Series, co-hosted by BioMed X Institute and the DKFZ Postdoc Network (PDN), with generous support from DKFZ German Cancer Research Center. 🧬 Speaker: Dr. Arnau Sebé-Pedrós 🗓 Date: Thursday, April 24, 2025 🕚 Time: 11:00 AM 📍 Location: DKFZ Communication Center, Im Neuenheimer Feld 280, Heidelberg Dr. Sebé-Pedrós, Associate Faculty at the Wellcome Sanger Institute, will present: “Early metazoan cell type diversity, evolution, and regulation” His research investigates how a single genome gives rise to diverse cell types and explores the evolution of gene regulatory mechanisms in early-branching animals. The talk will highlight recent findings on neuronal gene expression programs and the architecture of regulatory networks in basal metazoans—offering new perspectives on the evolution of multicellularity. We look forward to welcoming you to an insightful session at the intersection of evolutionary biology, genomics, and cellular regulation. #LunchTalkSeries #BioMedX #DKFZ #EvolutionaryBiology #RegulatoryGenomics #CellTypeDiversity #ResearchSeminar #LifeSciences #AcademicEvents #ResearchCollaboration

#WelcometoBioMedX 🌸 We are happy to welcome Fatemeh Amir Hashchi, our new research assistant in team TAP – New Strategies to Target Autoreactive Plasma Cells. 🌸 She is originally from Khuzestan, Iran, where she earned a bachelor’s degree in Cell and Molecular Biology from Shahid Chamran University of Ahvaz (Jundi Shapur). Later, she completed a master’s degree in Medical Virology at Health school, Ahvaz Jundishapur University of Medical Sciences, followed by a second master’s degree in Molecular Life Sciences at Friedrich Schiller University Jena, Germany. 🌸 Before completing her studies, she gained hands-on research experience during her master’s practicum and thesis at the Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute, within the Microbial Immunology group. Her work focused on characterizing the heterogeneity of the immune response to Candida albicans strains SC5314 and 101, exploring the interactions between innate and adaptive immune cells. 🌸 Welcome, Fatemeh! 💡 Are you interested in career opportunities at the interface between academia and industry? Take a look at the BioMed X Institute Career Space: https://bio.mx/career. Eleonora Melzi

🤝 Meet Top German Healthcare Innovators – Book Your B2B Meeting Now!   As part of the Healthcare Applications delegation, we’re bringing 5 strong companies of German pharma and biotech to Taiwan. Don’t miss your chance to connect directly with industry leaders through exclusive one-on-one B2B meetings from May 21 to 23.   This delegation trip, funded by the Federal Ministry for Economic Affairs and Climate Action under the market entry programme, brings together cutting-edge players in drug development, medical packaging, coating technology, cell culture, and more:   🔹 BioMed X GmbH (BioMed X Institute) – Biomedical research & drug discovery 🔹 HWI pharma services GmbH (HWI group) – Formulation, analytics & regulatory support 🔹 PRIMACYT Cell Culture Technology GmbH – Liver-related research products & medical device testing 🔹 ROHDE KG – Hygienic coatings for healthcare facilities 🔹 Sensoplast Packmitteltechnik GmbH – High-precision closures & medical devices   📅 Book your one-on-one B2B meeting now and explore partnership opportunities with Germany’s healthcare innovators. 🎯 B2B Meetings: May 21–23 (By appointment)   🔗 Learn more about the companies and secure your meeting slot – link in the comments! 🤝與德國醫療創新企業面對面交流──立即預約專屬B2B洽談！   作為德國應用醫療商務代表團的一部分，我們將攜手五家來自德國的強勢藥品與生技企業訪問台灣。這是您與產業領袖對接、共同探索合作契機的寶貴機會。一對一B2B洽談將於5月21日至5月23日舉行，採預約制。   本次代表團由德國聯邦經濟暨氣候保護部（BMWK）市場拓展計畫資助，聚焦在藥物開發、醫療包裝、塗層技術、細胞培養等領域的尖端企業。   🔹 BioMed X GmbH – 生物醫學研究與藥物開發 🔹 HWI pharma services GmbH – 劑型設計、分析與法規支援 🔹 PRIMACYT Cell Culture Technology GmbH – 肝臟相關研究產品與醫療器材測試 🔹 ROHDE KG – 醫療設施專用衛生塗層技術 🔹 Sensoplast Packmitteltechnik GmbH – 高精度瓶蓋與醫療裝置   📅 一對一B2B商務洽談時間：5月21日至5月23日（採預約制）   🎯 歡迎探索創新解決方案、拓展合作夥伴關係   🔗 活動詳情與預約洽談時段，請見留言區連結！   #PartnerInTaiwan #HealthcareInnovation #Biotech #MedicalTech #BusinessNetworking #B2BMeetings

🚀 Join us for the 2025 Ivy+ Just-In-Time Virtual Job & Internship Fair 🚀    We are thrilled to invite you to the upcoming virtual fair organized by Ivy+ Consortium place on April 10, 2025 between 1pm to 4pm EDT.   This is your chance to explore and learn about BioMed X Institute. Whether you are looking to be a part of our teams, explore upcoming opportunities or learn about BioMed X Institute, get your answers in the group or 1:1 session.  📆 We have the following open slots:  Group session - 1pm - 1:30 pm EDT  1:1 session - 1:30 pm EDT onwards ✅Why should you join:  - It’s completely online  - Learn about the existing and upcoming opportunities at BioMed X Institute  - Insights and clarity in the 1:1 session  - Great way to make connections   - Great way to expand your network 🌉 Learn about our newly launched XBridge Program—a unique opportunity for U.S.-based researchers affected by NIH funding gaps. Through this initiative, selected PIs can submit their existing NIH proposals to connect with potential pharma sponsors and continue their work at our BioMed X sites in Heidelberg or New Haven. Learn more during the fair!   ✨ Looking forward to seeing you there! ✨ #BioMedX #VirtualFair #JobOpportunities #CancerResearch #LifeScience 

🌉 Today we launch 𝗫𝗕𝗿𝗶𝗱𝗴𝗲: A Unique Matchmaking Program for U.S. Researchers Affected by NIH Funding Gaps🔴 We #StandUpForScience As researchers face unprecedented funding disruptions, we at BioMed X Institute are launching the XBridge Program to support U.S.-based principal investigators impacted by NIH grant terminations, delays, or freezes. How the XBridge Program Works 📂 Researchers can submit their existing NIH grant proposals through BioMed X’s global crowdsourcing platform Career Space (see link in comments below). 🧬 All research projects focusing on exploration of human disease biology, identification of novel therapeutic targets, or development of new therapeutic concepts in any human disease area are in scope. 🤝 Applications will be reviewed by BioMed X’s network of pharma partners, who may choose to sponsor individual research projects. 💡 Selected applicants will be invited to a pitch day, where they can present their research proposals directly to a panel of potential research sponsors from the pharmaceutical industry. This is not a grant, but a matchmaking opportunity to continue vital biomedical research through new channels of collaboration. Let’s keep vital biomedical research moving forward—𝑡𝑜𝑔𝑒𝑡ℎ𝑒𝑟. 𝗟𝗲𝘁’𝘀 𝘀𝘁𝗮𝗻𝗱 𝘂𝗽 𝗳𝗼𝗿 𝘀𝗰𝗶𝗲𝗻𝗰𝗲. 📍 Application deadline: June 29, 2025 🔗 Apply via our Career Space 📩 Questions? career@bio.mx Christian Tidona | Thomas Rueckle | Suchismita D. | John Lindner | Maria Morganti #StandUpForScience #XBridge #NIHfunding #BioMedX #ResearchCollaboration #LifeSciences #PharmaInnovation #BiomedicalResearch #InnovationEcosystem

Connecting with Future Scientists in New Haven Yesterday, our team had the opportunity to welcome Dr. Nagasree Garapati, Ph.D., PE and her students from the University of New Haven to our site in New Haven. We appreciated the engaging exchange as we showcased our research capabilities and discussed ongoing projects at the intersection of #academia and #biomedical #innovation. It was a pleasure to host such a curious and motivated group of students. Special thanks to Alicia Cutler and John Lindner for the warm welcome and for helping facilitate this visit. We look forward to continued dialogue between academia and industry to inspire the next generation of researchers. Gu Huan | Shue Wang | Nagasree Garapati, Ph.D., PE #LifeSciences #STEMEducation #ResearchCollaboration #Innovation #AcademicIndustryBridge

#WelcomeToBioMedX 🌴 We are happy to welcome Esma Dervisevic, our new postdoc in team BDB – Biomarker Detection in the Brain. 🔬 Esma is a bioengineer with a background in electrochemical biosensing. She completed her undergraduate studies in Genetics and Bioengineering in Istanbul, where she first began working on electrochemical biosensors. 🔬 She obtained her PhD from Monash University in Melbourne, Australia, where she developed microfluidic platforms for the continuous monitoring of biomarkers in cell culture media using both optical and electrochemical sensing techniques. 🔬 Before her current role, she spent three years at Proton Intelligence, a startup based in Australia, where she focused on the research and development of a wearable device for continuous potassium monitoring. Welcome to BioMed X, Esma! 💡 Are you interested in career opportunities at the interface between academia and industry? Take a look at the BioMed X Institute Career Space: https://bio.mx/career. Khulan Sergelen #ElectrochemicalBiosensing #MicrofluidicPlatforms #BiomarkerDetection #WearableDevices

🔉 Celebrating Collaboration: A Warm Welcome at ONO PHARMACEUTICAL CO., LTD. We are honored to have our Managing Director, Christian Tidona, hosted as a distinguished guest at the Ono Pharmaceutical Minase Research Institute near Osaka. With the German flag in the background, a member of the honorable Ono family, Mr. Isao Ono welcomed him in fluent German and led an insightful tour through the over 300-year history of Ono Pharmaceutical at the Ono Pharma Heritage Center. 🔬 This visit underscores the trustful collaboration between our BioMed X Institute and ONO PHARMACEUTICAL CO., LTD., united by a shared vision of advancing biomedical research through open innovation and cross-disciplinary collaboration. 🙏 We deeply appreciate the warm hospitality of our partners at Ono Pharmaceutical and look forward to jointly laying the groundwork for the next generation of targeted therapeutics. “𝘋𝘦𝘥𝘪𝘤𝘢𝘵𝘦𝘥 𝘵𝘰 𝘵𝘩𝘦 𝘍𝘪𝘨𝘩𝘵 𝘢𝘨𝘢𝘪𝘯𝘴𝘵 𝘋𝘪𝘴𝘦𝘢𝘴𝘦 𝘢𝘯𝘥 𝘗𝘢𝘪𝘯” (Corporate Philosophy of Ono Pharmaceutical). 📸 In the photo (from left to right): Daisuke Saito (Manager, Discovery Research Alliance), Hiroki Shioya (Associate Director, Research Alliance), Shingo Hotta (Associate Director, Research Center of Oncology), Kazuhiko Takeda (Director, Research Center Oncology), Christian Tidona (Managing Director, BioMed X), Isao Ono (Senior Partner, Ono Pharma Heritage Center), and Shintaro Mizote (Associate Director, General Affairs Section). Shingo Hotta, KAZUHIKO TAKEDA, Hiroki Shioya, Christian Tidona, Thomas Rueckle, Stefanie Bärthel, ONO PHARMA USA

🔬 𝗜𝗻𝘁𝗿𝗼𝗱𝘂𝗰𝗶𝗻𝗴 𝗧-𝗙𝗜𝗡𝗗𝗘𝗥 𝗮𝘁 𝘁𝗵𝗲 𝟲𝘁𝗵 𝗧𝗖𝗥-𝗕𝗮𝘀𝗲𝗱 𝗧𝗵𝗲𝗿𝗮𝗽𝗶𝗲𝘀 𝗦𝘂𝗺𝗺𝗶𝘁 𝗶𝗻 𝗕𝗼𝘀𝘁𝗼𝗻 We are excited to announce that John Lindner, Head of Immunology Discovery & Head of Research USA at BioMed X Institute, will be introducing T-FINDER at the 6th TCR-Based Therapies Summit in Boston on Wednesday, April 2, 2025. 𝗧-𝗙𝗜𝗡𝗗𝗘𝗥 (𝗧-𝗰𝗲𝗹𝗹 𝗙𝘂𝗻𝗰𝘁𝗶𝗼𝗻𝗮𝗹 𝗜𝗱𝗲𝗻𝘁𝗶𝗳𝗶𝗰𝗮𝘁𝗶𝗼𝗻 𝗮𝗻𝗱 (𝗡𝗲𝗼-)𝗮𝗻𝘁𝗶𝗴𝗲𝗻 𝗗𝗶𝘀𝗰𝗼𝘃𝗲𝗿𝘆 𝗼𝗳 𝗘𝗽𝗶𝘁𝗼𝗽𝗲𝘀 𝗮𝗻𝗱 𝗥𝗲𝗰𝗲𝗽𝘁𝗼𝗿𝘀), developed by Team #IAA at BioMed X Institute, is a modular, high-throughput system designed to functionally validate TCR:ligand interactions beyond computational predictions. By providing a plug-and-play platform for both HLA class I and II epitope discovery, this tool accelerates the development of next-generation #TCRbased #therapies with precision and reliability. 🔎 Key Highlights of His Presentation – "𝗦𝗲𝗹𝗳-𝗩𝗮𝗹𝗶𝗱𝗮𝘁𝗶𝗻𝗴 𝗧𝗼𝗼𝗹𝘀 𝗳𝗼𝗿 𝗙𝘂𝗻𝗰𝘁𝗶𝗼𝗻𝗮𝗹 𝗣𝗮𝗻-𝗛𝗟𝗔 𝗘𝗽𝗶𝘁𝗼𝗽𝗲 & 𝗧𝗖𝗥 𝗗𝗶𝘀𝗰𝗼𝘃𝗲𝗿𝘆" • Data-driven insights demonstrating the need for wet-lab validation/discovery methodologies that do not rely on predictive tools or unproven input • T-FINDER: A modular, plug-and-play system for high-throughput interrogation of putative TCR:ligand interactions for both class I and class II HLA-presented epitopes • ESTEL: An HLA-agnostic tool for identifying TCRs of interest across a set of putative ligands Join us as we showcase cutting-edge approaches to TCR discovery, driving the next wave of #precision #immunotherapy. 📌 Interested in booking a meeting with John during the summit or while in Boston? Feel free to reach out in the comments or via direct message: lindner@bio.mx.   #TCRSummit2025 #TCRDiscovery #Immunotherapy #FunctionalScreening #LifeSciences #BioMedX #ResearchInnovation #ImmunologyResearch #CellTherapy

📢 New Publication Alert 📢 Molecularly Responsive Aptamer-Functionalized Hydrogel for Continuous Plasmonic Biomonitoring We are excited to share our latest research on real-time, #continuous #drug #monitoring using aptamer-functionalized hydrogel (#Aptagel), now published in #JACS (Journal of the American Chemical Society). This innovative biosensor integrates Aptagel film with surface plasmon resonance (SPR) readout, enabling precise optical signal generation upon analyte binding. Notably, its anti-fouling properties make it highly effective in complex biological environments, paving the way for stable in vivo #biomonitoring of various #biomarkers. A huge congratulations to Soohyun Park (first author), Alice Gerber, Cátia Santa, and Group Leader Khulan Sergelen from Team #BDB for driving this research forward! This work is the result of a strong academic-industry #collaboration: 🔹 Pharma Partner: Boehringer Ingelheim – Bastian Hengerer (Industry Mentor) 🔹 Academic Collaborators: Jakub Dostalek, Ulrich Jonas, Heather Clark, Gizem A. 🔗 Read the full publication: https://lnkd.in/eTRt8Fhs #Biosensors #LifeSciences #PharmaInnovation #Biomonitoring #Aptamer #Hydrogel #BioMedX