BioMed X Institute’s Post

BioMed X Institute · 2025-03-28T15:20:45.132Z

🔬 𝗜𝗻𝘁𝗿𝗼𝗱𝘂𝗰𝗶𝗻𝗴 𝗧-𝗙𝗜𝗡𝗗𝗘𝗥 𝗮𝘁 𝘁𝗵𝗲 𝟲𝘁𝗵 𝗧𝗖𝗥-𝗕𝗮𝘀𝗲𝗱 𝗧𝗵𝗲𝗿𝗮𝗽𝗶𝗲𝘀 𝗦𝘂𝗺𝗺𝗶𝘁 𝗶𝗻 𝗕𝗼𝘀𝘁𝗼𝗻 We are excited to announce that John Lindner, Head of Immunology Discovery & Head of Research USA at BioMed X Institute, will be introducing T-FINDER at the 6th TCR-Based Therapies Summit in Boston on Wednesday, April 2, 2025. 𝗧-𝗙𝗜𝗡𝗗𝗘𝗥 (𝗧-𝗰𝗲𝗹𝗹 𝗙𝘂𝗻𝗰𝘁𝗶𝗼𝗻𝗮𝗹 𝗜𝗱𝗲𝗻𝘁𝗶𝗳𝗶𝗰𝗮𝘁𝗶𝗼𝗻 𝗮𝗻𝗱 (𝗡𝗲𝗼-)𝗮𝗻𝘁𝗶𝗴𝗲𝗻 𝗗𝗶𝘀𝗰𝗼𝘃𝗲𝗿𝘆 𝗼𝗳 𝗘𝗽𝗶𝘁𝗼𝗽𝗲𝘀 𝗮𝗻𝗱 𝗥𝗲𝗰𝗲𝗽𝘁𝗼𝗿𝘀), developed by Team #IAA at BioMed X Institute, is a modular, high-throughput system designed to functionally validate TCR:ligand interactions beyond computational predictions. By providing a plug-and-play platform for both HLA class I and II epitope discovery, this tool accelerates the development of next-generation #TCRbased #therapies with precision and reliability. 🔎 Key Highlights of His Presentation – "𝗦𝗲𝗹𝗳-𝗩𝗮𝗹𝗶𝗱𝗮𝘁𝗶𝗻𝗴 𝗧𝗼𝗼𝗹𝘀 𝗳𝗼𝗿 𝗙𝘂𝗻𝗰𝘁𝗶𝗼𝗻𝗮𝗹 𝗣𝗮𝗻-𝗛𝗟𝗔 𝗘𝗽𝗶𝘁𝗼𝗽𝗲 & 𝗧𝗖𝗥 𝗗𝗶𝘀𝗰𝗼𝘃𝗲𝗿𝘆" • Data-driven insights demonstrating the need for wet-lab validation/discovery methodologies that do not rely on predictive tools or unproven input • T-FINDER: A modular, plug-and-play system for high-throughput interrogation of putative TCR:ligand interactions for both class I and class II HLA-presented epitopes • ESTEL: An HLA-agnostic tool for identifying TCRs of interest across a set of putative ligands Join us as we showcase cutting-edge approaches to TCR discovery, driving the next wave of #precision #immunotherapy. 📌 Interested in booking a meeting with John during the summit or while in Boston? Feel free to reach out in the comments or via direct message: lindner@bio.mx. #TCRSummit2025 #TCRDiscovery #Immunotherapy #FunctionalScreening #LifeSciences #BioMedX #ResearchInnovation #ImmunologyResearch #CellTherapy

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