The document discusses common CSS mistakes to avoid, including: 1) Not distinguishing between IDs and classes when selecting elements. IDs are unique and classes can be reused. 2) Including unnecessary units like "px" when a value is zero. 3) Repeating CSS properties that can be combined, like setting each border side individually. 4) Including excessive whitespace which increases file size without benefit. 5) Not grouping identical styles for multiple elements to make updates easier. 6) Confusing the difference between margins, which are outside borders, and padding, which is inside borders.