This document provides instructions on how to create chained (interdependent) combobox selections using Glade and Ruby. It explains how to create a GUI with three comboboxes using Glade where the options in the second and third combobox depend on the selection in the previous combobox. It then provides the Ruby code to populate the comboboxes with data from a database using ActiveRecord and handle the changed signals to update the dependent comboboxes.