Muscular Dystrophy Association’s Post

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View profile for Sharon Hesterlee

EVP Chief Research Officer at Muscular Dystrophy Association

Regenerating lost muscle has long been one of the greatest challenges in neuromuscular disease research. Today, thanks to breakthroughs in regenerative science, we are closer than ever to making it a reality. At Muscular Dystrophy Association's inaugural Muscle Regeneration Summit last summer and the 2025 MDA Clinical & Scientific Conference this month, leading scientists, medical professionals, and patient advocates gathered to explore new frontiers in muscle restoration. The latest research is uncovering how stem cells—specifically muscle satellite cells—could be harnessed to repair and rebuild muscle tissue. Advances in the field have culminated in several planned clinical trials for muscular dystrophies by Somite-AI, Myogenica, Myopax amongst other efforts.     In our latest issue of MDA’s Quest Magazine, Andrew Zaleski , dives into these cutting-edge advancements and what they mean for people living with Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), myotonic dystrophy (DM), and other neuromuscular diseases.     Read more about how we’re driving progress in muscle regeneration:   https://lnkd.in/g64MvW9a

Hi Sharon, I hope your team is considering Lama2 CMD as well. I am a mother of a 1.5 year child who have been diagnosed with Lama2. We have founded Lama2 India and even connected with 52+ children across the country who are living with the same condition. We sincerely hope that any upcoming treatments or clinical efforts will include and consider the LAMA2 community as well. Looking forward with hope.

Wendy Selig

Founder & CEO at WSCollaborative LLC

2d

Great progress!

Patricia S.

Patient Engagement Lead/Advocacy/Territory Manager/Sr. Clinical Ed. specialist/Medical device/Patient Access/case management

1d

Thanks for sharing, Sharon

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Kegan Cassidy

Senior Agile Project Manager | Driving project success

1d

All the way down here in South Africa my wife is living with FSH MD, i watch (over the years) as her condition worsens 😔. Its encouraging to see information like this, thank you for sharing.

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Jyoti Bharadwaj

Genetic Research | Accounting | Circular Economist

2d

Hoping to see this move into clinics soon—really optimistic about its potential! Quick question: one of the ongoing challenges in Duchenne research is the hostile environment for stem cells, which often hinders engraftment. Are there any strategies being explored to overcome this and improve engraftment success? Looking forward to hearing your thoughts.

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This will be a game changer! Thanks Sharon!

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