LGC Standards’ Post

Explore the latest advancements in transporter science and modelling techniques by downloading our informative white paper here: https://lnkd.in/e46DDPft ⬇️ False positives in in-vitro toxicology and drug-drug interaction (DDI) studies continue to be a significant obstacle in drug development, leading to unnecessary clinical trials, increased costs, and delayed access to life-saving therapies. Recent advancements in transporter science—including the validation of biomarkers such as coproporphyrin I (CPI) and next-generation in vitro models like organ-on-a-chip—are transforming the landscape. These developments, combined with improved modelling techniques, enable more accurate predictions of toxicity and DDI scenarios. This white paper provides practical guidance for drug developers on how to integrate biomarker and assay data to enhance predictive reliability, in accordance with ICH M12 regulatory guidelines. #Whitepaper #DrugDevelopment #TransporterScience #InVitroToxicology #Biomarkers #PharmaceuticalResearch

  • No alternative text description for this image

To view or add a comment, sign in

Explore topics