Case Study: Managing Golden Retriever-Associated Uveitis and Glaucoma
Golden Retriever-Associated Uveitis (GRAU), also known as pigmentary uveitis, is a chronic and hereditary eye condition unique to Golden Retrievers. Recently, I encountered a challenging case that emphasized the importance of early diagnosis, effective treatment, and prevention to ensure the best outcomes.
The Case
A 7-year-old Golden Retriever presented with:
Persistent tearing (epiphora) and eye redness (episcleral injection).
Cloudy appearance in the eyes due to corneal edema and pigment deposition.
Blepharospasm (squinting) and signs of discomfort.
Elevated intraocular pressure (IOP) on tonometry (>30 mmHg).
Diagnostics
Slit-Lamp Examination: Detected aqueous flare and pigment deposits on the cornea.
Tonometry: Confirmed glaucoma with elevated IOP.
Ultrasound Imaging: Identified posterior segment changes and early lens opacity.
Treatment Protocol
Medical Management:
Anti-inflammatory Therapy: Prednisolone acetate 1% eye drops (1 drop every 6–8 hours).
IOP Control: Timolol 0.5% eye drops (1 drop every 12 hours) and Dorzolamide 2% (1 drop every 8 hours).
Pain Management: Gabapentin (10 mg/kg orally every 12 hours).
Surgical Intervention:
Planned for laser cyclophotocoagulation to control aqueous humor production, reducing IOP long-term.
Outcome
With consistent treatment, the dog's condition stabilized. Intraocular pressure normalized, and inflammation subsided, improving comfort and vision.
Prevention and Client Education
Regular Eye Exams: Advised routine IOP monitoring and annual eye checks for at-risk breeds.
Genetic Awareness: Educated on avoiding breeding dogs with GRAU history.
Early Intervention: Highlighted the importance of seeking veterinary care for early signs of redness, squinting, or tearing.
Golden Retrievers are a beloved breed, but they are prone to unique health challenges. With early diagnosis, aggressive treatment, and client education, we can improve outcomes and preserve their quality of life.
Have you managed a challenging case of uveitis or glaucoma in your practice? Share your insights in the comments! 🩺🐾
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