Two Sigma Ventures’ cover photo
Two Sigma Ventures

Two Sigma Ventures

Software Development

New York, New York 30,285 followers

About us

We back entrepreneurs doing big things with data. We invest in early-stage companies across many industries spanning enterprise SaaS, fintech, techbio, consumer tech, crypto and defi, and more. Two Sigma is proud to be an equal opportunity workplace. We do not discriminate based upon race, religion, color, national origin, sex, sexual orientation, gender identity/expression, age, status as a protected veteran, status as an individual with a disability, or any other applicable legally protected characteristics. The information presented in this profile is offered for recruiting purposes only and should not be used for any other purpose. As such, Two Sigma’s use of LinkedIn is not an offer to, or solicitation of, any potential clients or investors for the provision by Two Sigma of investment management, advisory or any other related services. No information posted by Two Sigma should be construed as investment advice, or as an offer to sell, or a solicitation of an offer to buy, any security or other instrument. All trademarks, logos, information and photos are ®/TM/© Two Sigma Investments, LP or its affiliates. All rights reserved.

Industry
Software Development
Company size
11-50 employees
Headquarters
New York, New York
Type
Partnership

Locations

  • Primary

    100 Avenue of the Americas

    New York, New York 10013, US

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Employees at Two Sigma Ventures

Updates

  • Two Sigma Ventures reposted this

    View profile for Nikhil Namburi

    Investor @ Two Sigma Ventures

    Don't Sell Work, Give It Away “Sell work not software” has been a common trope among VCs, but it seems to be aging quite poorly. The problem with this thesis is that it causes you to underwrite a TAM that’s roughly proportional to existing markets for human labor ($100Bs). But of course, customers won't pay "x% of human costs" in 7 years. They'll pay the prevailing rate of AI agents, which will be orders of magnitude cheaper than current human rates. My favorite new wave of startups is giving away agents at cost, with their actual revenue model predicated on adjacent offerings enabled by at-cost AI agents: 1) Financing - Credit: Offer agentic workflows for unstructured docs (e.g., invoices or inventory) at cost. Use that data to better price loans, inventory financing, etc. - Also applies to underwriting risk (insurance), equity (buying ownership), fraud (corporate cards), etc. 2) Marketplaces, Brokers, & Protocols - AI-native brokers: Refer to Jared Rosner's excellent piece. - Bonus points if non-users are precluded from participating in an industry, like Bloomberg IB. 3) Recommendation Systems - Having access to a customer’s docs could create a MUCH better ads, marketing, or co-selling service. 4) Vertical Integration with Operational Excellence - This also includes roll-ups and buyouts. Most VCs should stay away, as it requires a level of operational/financial sophistication that most early-stage investors are poorly equipped for. Of course, there are still opportunities for durable revenue by selling agentic software alone. But it’s difficult to imagine durability in agentic software revenue unless it's built on one of the following moats: 1) Too-Cheap-to-Replace - If the marginal cost per user is really small ($5-10), it's just an annoyance for the user to switch. - In this case, the number of potential users is all that matters. (Cursor?) 2) Physical Data Collection or Generation -Deploy proprietary sensors in the customer's environment/site that collect previously unmeasurable data. or -Generate novel datasets in-house. 3) Regulatory - Real-time policy adherence. (Valuable when the model providers can't incorporate policy updates quickly enough in their public API.) - Limited approved vendors. - Risk of fine or financial loss to the customer. 4) Platform -Allow (ideally non-software) 3rd-party services to build on your agentic workflows. There are other exceptions, so feel free to throw them in the comments! Last, but not least, there's brand & trust. Nothing new for me to say here. A lot of startups are claiming that they’ll be sticky due to the “moats” below, but these seem a lot weaker in an agent-centric world: 1) System of record 2) Cognitive switching costs (in the enterprise) 3) "Embedding deeply" in enterprise workflows If these moats do persist, they would strongly advantage incumbents, anyways. cc: Vin Sachidananda, PhD, Two Sigma Ventures Message me at nikhil@tsv.vc! https://lnkd.in/eH3dnnKY

  • Two Sigma Ventures reposted this

    View profile for Nicole DeTommaso
    Nicole DeTommaso Nicole DeTommaso is an Influencer

    Principal at Harlem Capital | Forbes30u30 | Providing insights to demystify the VC industry🪄

    VC Job Openings🪄 10 firms actively hiring right now. Check out this week's openings (Mar 20 - 26)👇 Andreessen Horowitz is hiring a Healthcare Investor. Location: n/a https://shorturl.at/JObK6 Two Sigma Ventures is hiring a Summer Intern. Location: NYC https://lnkd.in/eX6BSsqt Entrepreneurs First is hiring an Associate. Location: San Francisco https://lnkd.in/e_mqHCmZ Samvid Ventures is hiring an MBA Summer Associate. Location: NYC https://lnkd.in/eE493UXQ TenOneTen Ventures is hiring an Associate. Location: San Francisco https://lnkd.in/ebMi43nx Hico Ventures is hiring an Investor. Location: Palo Alto https://lnkd.in/eRsDWVkG Potencia Ventures is hiring an Impact Investment Analyst. Location: Colombia/Mexico/Brazil - Remote https://lnkd.in/eqE6pqRX Salesforce Ventures Impact Fund is hiring a Senior Analyst. Location: San Francisco https://lnkd.in/eyznkChE Workshop Venture Partners is hiring an Associate. Location: Remote https://lnkd.in/eYgaZ78G Arnold Ventures is hiring a Healthcare Analyst. Location: Washington, DC https://lnkd.in/eu9mJZzr --- 𝐃𝐨𝐧'𝐭 𝐡𝐚𝐯𝐞 𝐚 𝐭𝐫𝐚𝐝𝐢𝐭𝐢𝐨𝐧𝐚𝐥 𝐛𝐚𝐜𝐤𝐠𝐫𝐨𝐮𝐧𝐝? Here are creative ways to land a VA role even without a finance background: https://lnkd.in/dXK4VaqA 𝐍𝐞𝐫𝐯𝐨𝐮𝐬 𝐚𝐛𝐨𝐮𝐭 𝐕𝐂 𝐢𝐧𝐭𝐞𝐫𝐯𝐢𝐞𝐰𝐬? Here's an 8-step interview prep checklist to follow: https://lnkd.in/gADFwD5w ♻️ Repost to help someone in your network! #venturecapital #startup #founder

  • Two Sigma Ventures is hiring Summer Interns in NYC! We're looking for high-agency undergrad or grad students who are not just interested in startups but actively engaged in the community - individuals with existing founder relationships and firsthand ecosystem knowledge. As our intern, you'll help us: source deals by researching emerging tech trends, conduct market analysis and competitive research, create investment memorandums and pitch deck analyses, and support portfolio companies with projects and research. Here's what you'll get from us: 🚀 Visibility into the entire venture investment process, with opportunities to connect directly with our investors, portfolio founders, and the broader startup ecosystem. 🤝 Collaborative, no-ego team where you have access to every conversation, meeting, and pitch.  🌎 Exposure to a diverse portfolio spanning industries where data science and advanced computing are creating breakthrough innovations.  🔎 High level of autonomy and the ability to follow your interests and passions, including conducting a research project of your choosing. If this sounds like you, apply at the link: https://bit.ly/TSVintern

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  • Two Sigma Ventures reposted this

    View organization page for Anomalo

    17,754 followers

    Big news! Snowflake has announced a strategic investment in Anomalo- signaling that data quality is mission-critical for enterprises looking to unlock the potential of data and AI. This is a testament to Anomalo’s unique approach. Built specifically for the enterprise, our AI-powered approach to data quality monitoring goes beyond rules and basic data observability to automate data quality at enterprise scale. We’re building the future of data quality at Anomalo, with data quality across both structured and unstructured data to support all data teams and all data use cases from Analytics, ML, and Generative AI. With Snowflake by our side, we’re excited to continue building a more data-driven world: https://lnkd.in/gbEvbFsi

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  • We’re hosting our annual Salon on March 27th, a structured, four-sided debate on some of the thorniest topics in tech. And this year, we’re attempting to get to the bottom of a trillion dollar question; A company founded this year will be worth $1T within a decade. But in which sector will it rise? - AI Superintelligence - Infrastructure - Biotech & Healthcare - Consumer If you’re a builder or operator in one of these areas, come represent your sector and help us see the future through your eyes. We’ve got a few spots open, so make sure to RSVP below.

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  • Two Sigma Ventures reposted this

    View profile for Dina Radenkovic Turner

    Co-founder & CEO at Gameto - Redefining Female Reproductive Health

    ✨ Pioneering a New Era in Fertility Treatment ✨ I am thrilled to announce that Gameto has received FDA clearance to launch our Phase 3 clinical trial for Fertilo - the first iPSC-based therapy to enter this stage since Shinya Yamanaka’s Nobel Prize-winning discovery of induced pluripotent stem cells (iPSCs). This milestone represents a transformative step in our mission to revolutionize #reproductive medicine and improve the #IVF experience. What makes this even more special? Our small but mighty team. 🙌 This achievement didn’t come easy - it took countless hours, unwavering determination, and #teamwork. Every member of our team poured their heart and soul into this, and this FDA clearance is a testament to their brilliance and passion for transforming #fertility treatment. Why Fertilo Matters: 🔬 Built on Nobel Prize-winning technology, Fertilo uses iPSC-derived ovarian support cells (OSCs) to mature eggs outside the body, reducing hormone injections by 80% and shortening IVF treatment cycles from 10-14 days to just 2-3 days. 💉 Potential to disrupt a multibillion-dollar injection market that has remained unchanged since IVF’s inception, replacing an outdated, difficult process with an innovative, patient-first solution. 🩺 A safer, less invasive approach - minimizing risks like ovarian hyperstimulation syndrome and reducing the harsh side effects of high-dose hormone treatments. Our Phase 3 trial will launch soon across 15 sites in the U.S., evaluating key outcomes such as embryo development, pregnancy rates, maternal health, and live birth outcomes. Patients struggling with infertility for at least a year will be eligible, with follow-up support for those who do not achieve pregnancy initially. This milestone follows another historic achievement: the world’s first live human birth using Fertilo technology, which took place in December 2024 (https://lnkd.in/gUR_3pZ3). Now, with FDA clearance for our Phase 3 study, we are excited to bring a faster, safer, and more accessible fertility solution to families worldwide. 🚀 The future of fertility is here. Stay tuned for trial updates and site locations across our channels. Read the Endpoints News article: https://lnkd.in/gHJt-icg #IVF #iPSC #Gameto #ClinicalTrials #WomensHealth #ReproductiveMedicine

  • Two Sigma Ventures reposted this

    View profile for Lukas Schulte

    Cofounder, CEO at SDF Labs

    Two years ago, I founded SDF Labs with my father Wolfram Schulte and our two phenomenal co-founders Michael Y. Levin and Elias DeFaria. We had a bold vision; to bring deeper SQL understanding, formal reasoning, and static analysis to data development. In other areas of software engineering precise error reporting, dependency tracking, and optimized code generation are powered by advanced tooling grounded in formal semantics. SQL tooling has long been left behind. Our mission has been to bridge that gap and redefine what's possible for SQL developers. I’m beyond excited to share that dbt Labs has acquired SDF Labs! While dbt’s capabilities are so comprehensive as to drive an entire ecosystem, it has historically been limited in one fundamental way: dbt only understands SQL statements only as a series of strings. Today, that changes. We anticipate bringing the full suite of SDF’s static analysis capabilities, speed, and scalability into the dbt ecosystem. 🚀 To read more on that, check out Tristan Handy's post here https://lnkd.in/gbYUxj-E I have so many people and institutions to thank for making this possible. Most importantly to the SDF team; thank you for your drive, dedication, and endless creativity. One chapter is closing, but we’re turning the page onto something even brighter, bolder, and more exciting.

  • Two Sigma Ventures reposted this

    For the first WIN/WIN episode of 2025 (which happens to be our 125th episode!) we are joined by Frances Schwiep, Partner at Two Sigma Ventures, who is also a master at systems thinking for anything and everything. Tune in to hear Frances’ evolution of her understanding of risk, the importance of independent thinking, and how she applies it as a leader in the innovation and venture capital industry. Links:  * Apple: https://lnkd.in/e9YYg-za  * Spotify: https://lnkd.in/e8mXSaUu Listen for advice on: * The pros and cons of traditional vs. corporate venture capital  * How women can create their own measuring sticks for success * Creating an equitable and strategic investment decision mechanism  * Ways to understand and engage with new technologies and innovations (such as AI) Zoia Kozakov

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  • TSV portfolio company Distributional was just put on Built In's 2025 best startups to work for remotely (and in SF) list! Perfect time to share that they're hiring for 2 roles 🔥 Distributional: Building the modern enterprise platform for AI testing to make AI safe, reliable, and secure. 1️⃣ Senior Front End Software Engineer (4+ years of experience, remote) 2️⃣ Senior Full Stack Software Engineer (4+ years of experience, remote) Apply here: https://lnkd.in/e4mgiMDu

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  • Two Sigma Ventures reposted this

    View profile for Scott Clark

    Cofounder/CEO of Distributional. Former VP/GM at Intel, Former CEO/co-founder of SigOpt (Acquired by Intel)

    I'm proud to be named one of 33 leaders on Forbes Technology Council's Top AI Founders To Watch in 2025. It's an honor to be included among so many other great founders in the field. You can check out the full list here: https://lnkd.in/gDe8HmQR

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