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How has Aescape turned a robotics platform into a brand consumers connect with? In this clip, Eric Litman explains how Aescape focused on designing a seamless, consumer experience, not just a functional robotic solution. From intuitive app-based booking to consistent in-person treatments, the team built a platform that feels more like a modern wellness service than a traditional medical device. Eric’s full LSI USA ’25 Fireside Chat, “Wellness 3.0: Building and Scaling a Robotics Startup in a New Era of Well-Being,” is now available on our website and YouTube channel. This conversation explores:  • Identifying unmet needs and the founding story of Aescape • Raising capital in and through turbulent and challenging market conditions • Contrarian thinking in pursuing an untapped market opportunity with advanced robotics • “Founder mode" and what it takes to build a winning culture, attract and develop talent • Go-to-market and develop business in opaque channels like gyms, professional athletics, hotels, etc. Stay tuned on our website, YouTube, and LinkedIn as we continue rolling out more keynotes, panels, workshops, and presentations from LSI USA ’25. #LSIUSA25

As our team and community gear up for LSI Asia ‘25 this June, excitement is already building for what’s next in London this September. With five months to go, LSI Europe '25 is drawing strong interest from investors and strategics around the world, reflecting the strength of the community and the quality of connections that define our events. Our focus has always been on curating the right mix of capital and innovation. It’s why we’ve built lasting relationships with active VCs, PEs, and CVCs, and why they continue to return year after year. Here’s a preview of who’s attending: • Harry Stebbings — Founder, 20VC • Murielle Thinard McLane — President & Managing Partner, Intuitive Ventures • Antoine Papiernik — Chairman & Managing Partner, Sofinnova Partners • Bibi Sattar Marques — Partner, Buenavista Equity Partners • Christopher Shen — Partner, Novo Holdings • Roberta Ferrari — Managing Director, EQT Life Sciences • Virginia Giddings — Vice President, Exploration, Edwards Lifesciences • Dan Sheehan — Vice President, Venture Capital, Medtronic • Dr. Irit Yaniv — Founding Partner, Almeda Ventures If you're looking to connect with hundreds of industry-leading investors and strategics, LSI Europe ‘25 is the place to do it. Ready to join us at LSI Europe ‘25? Our hotel room block at the JW Marriott Grosvenor House London is expected to reach capacity well in advance. Secure your spot on our website today to ensure you get the best rate and secure a hotel room onsite before they’re sold out.

Buenavista Equity Partners (formerly GED Capital) is an independent asset manager operating in the lower mid-market segment since its founding in 1996. The firm currently manages approximately €1 billion across Private Equity, Venture Capital, and Infrastructure investment vehicles. With a robust ecosystem of over 400 domestic and international investors, including pension funds, funds of funds, insurance companies, family offices, corporations, and financial institutions, Buenavista has established itself as a key player in the investment landscape. Buenavista Ventures, the firm’s venture capital division, focuses on supporting startups and entrepreneurs driving technological and digital innovation. As of 2023, it manages €150 million across two funds: • Buenavista Ventures (Spain): A €50 million fund dedicated to Series A (or pre-Series A) investments in Spanish startups within the digital sector, including software, fintech, e-commerce, and artificial intelligence. To date, this fund has backed 16 companies. • Buenavista Tech Seed (Portugal): A €100 million fund focused on Seed (or post-Seed) investments in Portuguese startups with significant R&D activity, certified by the Portuguese National Innovation Agency (ANI). Key sectors include Health Tech, Biotech, Clean Tech, and digital innovation, with six companies currently in its portfolio. Join us in welcoming Bibi Sattar Marques, Partner & Board Member at Buenavista Equity Partners Portugal. In 2017, she took on the challenge of developing the Venture Capital arm of a financial entity, where she played a pivotal role as Partner and Board Member. Over four years, she spearheaded the creation of the entity’s first nine venture capital funds, amassing over €100 million in assets under management and positioning the firm as a key player in the space. In 2021, Bibi joined BV Group as a Partner and Board Member of BV Ventures Portugal to expand the firm's venture capital presence and further strengthen its leadership across the Iberian market. Want to get involved at LSI Asia ‘25? Registration, applications for presenters, sponsorship opportunities, and our special hotel block rates are still open. Secure your spot today to join us at LSI Asia ‘25 on June 10th-13th at The Ritz-Carlton, Millenia Singapore.

Hot off the press! The latest edition of our weekly newsletter The Memo, featuring Dr. Oriol Iborra Egea, Co-Founder & CEO of NIMBLE Diagnostics, is out now! Under the direction of Co-Founder and CEO Dr. Oriol Iborra Egea, NIMBLE Diagnostics is creating a new frontier in implant monitoring and vascular care. With a non-invasive, microwave-based diagnostic device designed to monitor implanted stents in real time, NIMBLE is solving a long-standing blind spot in cardiovascular care: knowing what’s happening inside a stent without having to go back inside the body. “We implant a stent, we send the patient home, and we assume everything’s fine—until it’s not,” said Iborra. “We’ve built a way to monitor that stent non-invasively, quickly, and safely—before a serious event occurs.” From a research project in Barcelona to a fast-moving medtech startup with international ambitions, NIMBLE Diagnostics is on a mission to redefine how clinicians follow up with patients after stent implantation—and to prevent life-threatening complications before they happen. Continue Reading: https://lnkd.in/gZqKzb_V Oriol Iborra Egea has been selected to present at LSI Europe ‘25 this September 7th-11th in front of hundreds of global medical technology companies. Join us in welcoming Iborra to the event in London, where he will share the latest updates on NIMBLE Diagnostics’ technology and development.

With Edwards Lifesciences receiving CE Mark for the Sapien M3 Mitral Valve Replacement System, our analysts believe the Mitral Valve Market is at a significant inflection point. In fact, we're forecasting global procedural volumes in this space to nearly double within five years, from approximately 60,000 in 2024 to 120,000 by 2028 (23.9% CAGR). This week's edition of The Numbers — our weekly, no-fluff series with market data and insights from LSI's trusted Market Intelligence team — dives into the first-of-its-kind Sapien M3, the landscape in transcatheter mitral valve replacement (TMVR), the numbers driving this space from Market Intelligence, by LSI, and the companies we're watching closely. Capstan Medical | Tioga Cardiovascular | InnovHeart | Sutra Medical, Inc. Subscribe to The Numbers here on LinkedIn for weekly market intelligence, and let us know what you'd like to see covered next. Looking for deeper data on the Cardiovascular Market? Get in touch with our team to access our executive-ready TMVR Market Snapshot (available now) and our full Cardiovascular Package, including Global Procedure Volumes, Private Company and Deal Tracking, Market Sizing and More https://lnkd.in/eCmNzh2z PS - Want to hear directly from global strategics and investors like Dan Lippis, Vy Tran, Warren Wang, Greg Garfield and more? They'll be at LSI Asia '25 in Singapore, Jun 10-13. See who's joining and secure your spot today. lsiasiasummit.com

Spring is in full swing, and so are the LSI Alumni. This week, the LSI Alumni secured regulatory approvals, appointed new executives, welcomed new board members, and much more on the road to LSI Asia ‘25. Your 60-second news recap: Adagio Medical Holdings — Todd Usen → Received FDA Breakthrough Device Designation for its vCLAS™ Cryoablation System Alesi Surgical — Dominic Griffiths → Awarded the CE Certificate for its Ultravision2 surgical smoke management system. Arsenal Medical — Upma Sharma, PhD → Appointed Ray Baker, M.D., to its Board of Directors Atmo Biosciences — Malcolm Hebblewhite → Secured full ownership of its foundational patent portfolio for the Atmo Gas Capsule through an IP assignment agreement with RMIT University. Berg Capital Partners — Josh Berg → Partnered with Hemeo to serve as Fractional CFO and capital raise advisor Dova Health Intelligence — Solveig Johannessen → Rebranded from Satisfai Health to Dova Health Intelligence EBR Systems — John McCutcheon → Received FDA approval for the WiSE System, the world’s first and only leadless left ventricular endocardial pacing (LVEP) device for cardiac resynchronization therapy (CRT). Eclipse Regenesis — Andre Bessette → Enrolled and treated the first pediatric patient in its clinical study for short bowel syndrome (SBS) at Cincinnati Children’s Hospital. Egg Medical — Robert Wilson → Announced $14.3M in financing to support the commercialization of its EggNest shielding system EndoShunt Medical — Tyler Zanon → Appointed Michael Nagel as its new Chairman of the Board Hy2Care — Leo Smit, Sanna Severins → Received FDA IDE approval to initiate U.S. clinical trial for the CartRevive® hydrogel implant for cartilage repair. Lenoss Medical — Dom Messerli, MBA → Completed its 175th surgical procedure using the OsteoPearl™ biological allograft implant for vertebral compression fractures. LightHearted AI → Co-founders Lucrezia Cester, PhD and Dilip Rajeswari were featured in Forbes 30 Under 30 Minze Health → Appointed LSI Alumni Steffen Hovard as Executive Board Chair to help accelerate the company’s mission of advancing digital home health solutions. Neurosom — Viral Sheth → Received FDA 510(k) clearance for NEAT (Neurosom™ EEG Assessment Technology) medical device software. OSSTEC → CEO & Founder Maxwell Munford was featured in the Forbes 30 Under 30 list. Phagenesis → Appointed Marc Korenberg as Chief Financial Officer SPRIG Equity — Rebecca Raabe → Announced the final close of its inaugural fund with $50M in assets under management, marking a major milestone for SPRIG Equity’s mission to improve patient outcomes through transformative medtech investments. THINK Surgical — Stuart Simpson → Announced the first procedure using Maxx Orthopedics’ Freedom Total Knee implant with THINK Surgical’s TMINI Miniature Robotic System. Congratulations to all the LSI Alumni who made major news this week!

What was the founding journey behind Eric Litman’s founding of Aescape? In this clip, Eric Litman explains how his own recurring pain and frustration with inconsistent massage experiences sparked the idea for Aescape. Backed by investor interest and spurred on by those who said it couldn’t be done, he set out to build a robotics solution rooted in emerging trends around automation and human performance. Eric’s full LSI USA ’25 Fireside Chat, “Wellness 3.0: Building and Scaling a Robotics Startup in a New Era of Well-Being,” is now available on our website and YouTube channel. This conversation explores:  • Identifying unmet needs and the founding story of Aescape • Raising capital in and through turbulent and challenging market conditions • Contrarian thinking in pursuing an untapped market opportunity with advanced robotics • “Founder mode" and what it takes to build a winning culture, attract and develop talent • Go-to-market and develop business in opaque channels like gyms, professional athletics, hotels, etc. Stay tuned on our website, YouTube, and LinkedIn as we continue rolling out more keynotes, panels, workshops, and presentations from LSI USA ’25. #LSIUSA25

Now Available: The full Signature Series, “To Build or To Buy? Stryker's Thesis for AI, Robotics, and Growth” with Spencer Stiles, Group President of Orthopaedics and Spine at Stryker, in conversation with Emily West, Managing Director at Goldman Sachs. Spencer oversees Stryker’s Joint Replacement, Trauma and Extremities, and Spine businesses as well as the Digital, Robotics, and Enabling Technologies organization. He is also directly responsible for Europe, the Middle East, Africa, Latin America, and Canada, as well as Stryker’s enterprise M&A function, inclusive of strategic deal rationale and capital deployment. Most recently, Spencer established the Global Real Estate and Facilities organization, further aligning Stryker’s footprint strategy to operating principles. Watch Here: https://lnkd.in/gy3tnTAz Stay tuned as we continue rolling out more keynotes, panels, workshops, and presentations from LSI USA ’25 in the days and weeks ahead on our website, YouTube, and LinkedIn. #LSIUSA25

Continuing our ABCs of LSI USA ‘25 — R is for “Real World Evidence” Earlier this year, Caresyntax announced two major partnerships with Roivios, Ltd. and Qaelon Medical, signaling a bold step forward in leveraging real-world evidence (RWE) to transform healthcare. These collaborations are set to deepen the application of surgical intelligence and real-world data (RWD), driving actionable insights that improve patient outcomes, optimize clinical workflows, and inform strategic decisions across the healthcare ecosystem. At LSI USA ’25, we hosted a fireside chat with executives from Caresyntax, Roivios, and Qaelon Medical. Titled “Real World Evidence as Commercial Strategy for Startups and Strategics,” the session explored how RWE is being leveraged to drive innovation in healthcare and reshape commercialization strategies across the industry. Featured Speakers: • Bruce Ramshaw — Chief Medical Informatics Officer, Caresyntax • John Erbey — CEO, Roivios, Ltd. • Liam J. Burns — CEO, Qaelon Medical • Henry Peck (Moderator) — Chief Business Officer, LSI Stay tuned for the full video release of this fireside chat, plus more keynotes, panels, workshops, and presentations from LSI USA ’25 coming soon. PS: Registration is now open for LSI USA ‘26 next March 16-20 in Dana Point, California. Secure your spot early to take advantage of our best rates and have first priority for our hotel room block.

"We will very likely see the automation of almost every physical task we know of today, plus countless new ones we didn’t know could be automated.” — Eric Litman, Founder & CEO, Aescape Eric’s LSI USA ‘25 Fireside Chat, “Wellness 3.0: Building and Scaling a Robotics Startup in a New Era of Well-Being” is now available: https://lnkd.in/gRQHcBtZ This conversation explores:  • Identifying unmet needs and the founding story of Aescape • Raising capital in and through turbulent and challenging market conditions • Contrarian thinking in pursuing an untapped market opportunity with advanced robotics • “Founder mode" and what it takes to build a winning culture, attract and develop talent • Go-to-market and develop business in opaque channels like gyms, professional athletics, hotels, etc. Stay tuned on our website, YouTube, and LinkedIn as we continue rolling out more keynotes, panels, workshops, and presentations from LSI USA ’25 in the days and weeks ahead. #LSIUSA25