Aliri Bioanalysis

We are proud to share that our colleague Corinne Ramos, Ph.D., will be presenting a scientific poster at the AACR Annual Meeting 2025, highlighting exciting research that is game-changing for our sponsors’ drug development programs: 🧪 Spatially resolved effects of oligonucleotide therapeutics on cellular phenotypes in cancer tissues | Monday, April 28 from 2:00pm-5:00pm (Section 28, Board 8, Poster 3100) Not attending AACR? View this poster after the show in our resource library: https://lnkd.in/esrcEcvP #AACRAnnualMeeting2025 #Spatial #ScientificPoster #CRO

Corinne Ramos, Richard Egolf, and I had a blast visiting clients in #SanDiego and #SanFrancisco this week. It was so engaging to learn more about the cool science propelling our clients' #therapeutics and how Aliri Bioanalysis is positioned to help #derisk and #accelerate their #DrugDevelopment programs. #BioAnalysis #Spatial #Omics #Biomarkers

🕑 Need quick bioanalytical support for your most challenging programs? We can handle it! When timelines are tight and stakes are high, our team has the expertise needed to get decision-making data in your hands fast, so you can hit your next milestone. In a recent interview for Drug Development & Delivery online, Shane Karnik, Sen­ior Laboratory Director at Aliri Bioanalysis shares, “We are quite used to developing and validating custom assays for sponsors, usually in a matter of days, to keep their development projects on track.” Reach out to learn more about how our experienced team of scientists can work within your timeline to help advance your large or small molecule quickly. https://lnkd.in/e_WYncRT #CRO #Bioanalysis #ScienceStrong #CustomAssay #SmallMolecule #LargeMolecule

The Aliri team is looking forward to exhibiting at New Jersey DMDG’s Spring Symposium, in Somerset, New Jersey, tomorrow, April 23rd.  Join our colleagues Alexandra Martin and Erica Mulhern for a day of meaningful discussion on the topics of novel drug characterization, regulatory filing strategies, and the role of endogenous biomarkers. We hope to see you there!  Register for the event: https://lnkd.in/ega8kps6

🧬 5 Solutions for your ADC Therapeutic We are proud to be at the forefront of bioanalytical support for Antibody-Drug Conjugates (#ADCs), one of the most promising modalities in targeted cancer therapy. From spatial multi-omics to whole-body PK and immunogenicity, to GLP and GCLP bioanalysis, our team delivers the robust, regulatory-ready data you need to accelerate your drug development program from discovery through the clinic and beyond. Unlock the full potential of your ADC with Aliri’s end-to-end ADC solutions:  👉 1. Target Identification:  ✅ Spatial Transcriptomics – Maps the co-expression of candidate targets within specific tissue compartments, while revealing spatial heterogeneity across tumor regions. critical for ADC efficacy. ✅ Spatial Proteomics – Confirm membrane localization at single cell resolution and measure the co-localization of target and co-targets in tumor epithelial cells.     ✅ Data Analysis – Co-expression correlation, therapeutic window and target surface density. 👉 2. Drug Discovery:  ✅ Whole-body PK - Confirm target organ exposure, anticipate possible atypical DRM accumulation, and support decision-making in dose/formulation selection  ✅ Regulated and Non-Regulated BioDistribution 👉 3. Toxicokinetics: ✅ GLP Bioanalysis  ✅ Standardized approach for analysis of Human IgG-based mAb’s within preclinical matrices 👉 4. Pharmacokinetics: ✅ GCLP Bioanalysis  ✅ Non-proprietary assays to characterize the most commonly employed warheads 👉 5. Immunogenicity: ✅ Collaborate with the leader in immunogenicity assays; able to provide single point-of-contact for full suite of services  ✅ Single-cell view of the immune response to ADCs, enabling early detection of immunogenicity risk and immune-related toxicity.    Reach out to learn how we can support your drug development program: https://lnkd.in/eK7mFCFu #GLP #GCLP #ADC #AntibodyDrugConjugates #Immunogenicity #Pharmacokinetics #PK #Toxicokinetics #TK #DrugDiscovery #TargetIdentification #SpatialOmics #Transcriptomics #Proteomics

🧬 As pioneers in the bioanalysis of small and large molecules, we are passionate about identifying and validating the appropriate method to accurately determine the concentration and the bioactivity of your drug over time.  Our highly skilled team of scientists have over 30 years of experience optimizing the latest available research and cutting-edge platforms to provide you with actionable data that will accelerate your development program. 👉 Download this helpful infographic to learn how we determine the right bioanalytical method for your molecule: https://lnkd.in/eSUh-bpk #SmallMolecule #LargeMolecule #CRO

🌍 Get to Know our Global Laboratories! Aliri’s three global laboratories are proudly positioned to support pharma and biotech companies worldwide, providing advanced bioanalytical and spatial multi-omics solutions to industry challenges. Our passionate and highly knowledgeable scientists at our Colorado, Utah, and France locations have over 30 years of experience helping customers select the optimal platforms and best methods for their drug development programs, with each lab providing innovative services and capabilities that are unique to each other and unmatched in our industry. 📌Colorado Springs, CO: Specializes in the quantitative analysis of complex small molecule modalities, protein biologics, and biomarkers, leveraging cutting-edge analytical and business technologies such as LC-MS 📌Salt Lake City, UT: Pioneers in the quantitative analysis of oligonucleotides, utilizing a wide array of technical platforms and analytical methods including LC-MS and HRAM-MS 📌Lille, France: Industry leaders in spatial multi-omics services for translational and early-stage clinical research Reach out to speak with one of our many experts today: https://lnkd.in/ephEDrgT #CRO #Colorado #Utah #France #Bioanalysis #SpatialOmics

Case Study: What is causing limited bioavailability? Limited bioavailability can be difficult to diagnose, as there are many possible contributing factors including low absorption, heavy metabolism at an early stage in the gut, and first-pass metabolism in the liver.  In the below case study, Aliri employed our new label-free method combining whole-body QMSI and plasma LC-MS/MS to uncover the reason for limited bioavailability.  Watch the full webinar or reach out to learn how our experts can use Whole-Body PK to enable enhanced decision-making as you advance your development program.  https://lnkd.in/egSbcs_z #Bioavailability #Pharmacokinetics #WholeBodyPK #CRO #Bioanalysis #SpatialOmics Mathieu Gaudin

🚨 Upcoming Exhibit: AACR Annual Meeting 2025 We're pleased to announce that we will be exhibiting at the AACR Annual Meeting 2025 this month in Chicago from April 27-30! Join David Good, Ph.D. and Corinne Ramos, Ph.D., at booth #4741 to explore how Aliri is de-risking oncology research by pairing cutting-edge bioanalysis and spatial-omics solutions with AI to enhance candidate selection and predict patient outcomes. 👉 Meet our experts  👉 Learn about our latest capabilities  👉 Explore 2 scientific posters  👉 Discover how we can partner to accelerate your preclinical and clinical oncology drug development programs to help bring life-changing therapies to patients faster.    Reach out to schedule a meeting with our team at the show: https://lnkd.in/ekHNDb59 #AACRAnnualMeeting2025 #CRO #Bioanalysis #Oncology #SpatialOmics American Association for Cancer Research

📒 Scientific Poster: Selection and Evaluation of Hybridization Capture Probes for LC/MS Analysis of Oligonucleotides Last week at WRIB 2025 in New Orleans, LA, our colleague, Scott Reuschel shared an exciting scientific poster illustrating how he and his team implemented an alternate bioanalytical approach when conducting LC/MS analysis of oligonucleotides that can be used in cases where the LNA capture probe may produce interference to the oligonucleotide being analyzed.  Download the scientific poster here to learn more about the technique: https://lnkd.in/eBeniSKM #WRIB #ScientificPoster #CRO #Bioanalysis #Oligo #Hybridization