A new and rapid method for epistaxis treatment using injectable form of tranexamic acid topically: a randomized controlled trial
Methodology Score: 2/5 Usefulness Score: 3.5/5
Zahed R, Moharamzadeh P, Alizadeharasi S, Ghasemi A, Saeedi M.Am J Emerg Med. 2013 Sep;31(9):1389-92
Abstract Link
This single centre, ED based, parallel group randomized control trial found that the topical application of an injectable form of tranexamic acid (TXA) was better than anterior nasal packing (ANP) for halting bleeding within the first 10 minutes (ARR=40%, P=<0.001) and discharging the patient from the department within the first 2 hours (ARR=89%,P=<0.001). The DEM journal club identified several errors in the paper which compromised the validity of the results; however, the overall cost effectiveness (500mg TXA at The Ottawa Hospital = $5.90) and the potential for significantly decreasing patient discomfort made this low-risk intervention very appealing to attendees. By:Dr. Nicholas Costain (Presented January 2014)
Epi lesson: p values in baseline characteristic tables
Whether or not to present p values in Tab…
Zahed R, Moharamzadeh P, Alizadeharasi S, Ghasemi A, Saeedi M.Am J Emerg Med. 2013 Sep;31(9):1389-92
Abstract Link
This single centre, ED based, parallel group randomized control trial found that the topical application of an injectable form of tranexamic acid (TXA) was better than anterior nasal packing (ANP) for halting bleeding within the first 10 minutes (ARR=40%, P=<0.001) and discharging the patient from the department within the first 2 hours (ARR=89%,P=<0.001). The DEM journal club identified several errors in the paper which compromised the validity of the results; however, the overall cost effectiveness (500mg TXA at The Ottawa Hospital = $5.90) and the potential for significantly decreasing patient discomfort made this low-risk intervention very appealing to attendees. By:Dr. Nicholas Costain (Presented January 2014)
Epi lesson: p values in baseline characteristic tables
Whether or not to present p values in Tab…