PREMSTEM

Register by 20 April for the PREMSTEM Conference! Join members of the international scientific and medical communities in Barcelona this May to discover and discuss the latest research related to neonatal brain repair. Tickets for the 2.5 day event are €50 for online attendance and €250 if you'd like to come in person ➡️ https://lnkd.in/eTSfRBaz We look forward to seeing you there! #premstem #h2020 #premstemconference #research #conference #registration #RegisterNow #barcelona #neonatology #stemcells #cocreation #preterm

Bringing you the latest programme for the PREMSTEM Conference (13-15 May 2025) in Barcelona. Don't miss the opportunity to learn about the latest in neonatal research taking place across the globe! Registrations close on 20 April for in person participation ➡️ https://lnkd.in/eTSfRBaz #premstem #h2020 #premstemconference #research #conference #registration #RegisterNow #barcelona #neonatology #neuroscience #stemcells #cocreation #preterm

World Health Day kicks off a year-long campaign on maternal and newborn health - a topic that is close to our heart in the PREMSTEM team! The campaign called 'Healthy beginnings, hopeful futures' urges governments and the health community to ramp up efforts to end preventable maternal and newborn deaths, and to prioritise women’s longer-term health and wellbeing. PREMSTEM partner GFCNI - Global Foundation for the Care of Newborn Infants connects families, healthcare professionals and researchers in the joint goal of advancing the health and quality of care for newborns and their families. Their vision is for a future in which every baby receives the right care at the right time in the right place. On World Health Day, take a look at their information on maternal health ➡️ https://lnkd.in/eeXhrDA5 #premstem #h2020 #maternal #health #neonatology #childbirth #pregnancy #HopefulFutures #HealthForAll #OneWorldMovement #WorldHealthDay

Cora Nijboer, Ivo Bendix and Bobbi Fleiss are inviting submissions for a Cells Special Issue: Perinatal Brain Injury—from Pathophysiology to Therapy. Submit by October 2025. Learn more ➡️ https://ow.ly/qIG850VkBta This Special Issue aims to collect high-quality original manuscripts and reviews covering recent biomedical or clinical findings related to perinatal brain injuries, including new pharmacological or cell-based regenerative approaches to ameliorate the long-lasting deleterious consequences for brain development. #premstem #h2020 #callforpapers #cells_mdpi #perinatalbrain #neuroprotection #neuropathology #neonataology #neuroscience #pretermbirth #hypoxia #ischemia #hyperoxia #regenerativetherapies #stemcells Cells MDPI | RMIT STEM College | UMC Utrecht

Speakers at the PREMSTEM Conference are coming from far and wide! We can't wait to welcome members of the international scientific community to Barcelona this May to share research into neonatal brain repair. Read speaker bios and find a link to register ➡️ https://lnkd.in/ekJFWUMz #premstem #h2020 #premstemconference #speakers #neonatology #brainrepair #brain #neuroscience #research #barcelonaevent #barcelona

Bobbi Fleiss and PhD candidate Victor Mondal from the Perinatal Brain Injury Lab at RMIT University are attending the PSANZ Congress this week in Brisbane, Australia. Bobbi presented two posters on behalf of her student, Md Munnaf Hossen. Victor presented 'Innovative Hydrogel Therapy: A Novel Approach for Neonatal Stroke Treatment'. Neonatal stroke occurs within the first 28 days of life. It can lead to long-term medical conditions such as cerebral palsy and epilepsy. Victor and the team developed a rat model of neonatal stroke and determined whether a functionalised hydrogel can repair injury and improve function. They found the model to produce a motor cortex lesion and functional deficits that is reduced by the functionalised hydrogel effectively. Catch Bobbi at the PREMSTEM Conference where she's organising the session 'Novel and innovative approaches to screening' ➡️ https://lnkd.in/eTSfRBaz #premstem #h2020 #premstemconference #perinatology #perinatalhealth #PSANZ2025 RMIT STEM College

Lotte Smeets is a PhD student at the MERLN Institute and the Department of Paediatrics at Maastricht University where she is supervised by Sabine van Rijt, Tim Wolfs and Daan Ophelders. Together they are tracing the human mesenchymal stem cells that we use in PREMSTEM and unravelling their behaviour after administration in preclinical models of preterm birth. Thank you to Lotte for this image of nanoparticles and the nanoparticle-labelled MSCs. Lotte says that a major challenge in the clinical translation of MSC-based therapies is a limited understanding of how MSCs are distributed in the body. Tracing methods that can quantify the distribution of MSCs are needed to guide a more successful clinical translation of MSC-based therapies. "We synthesise gold nanoparticles containing a mesoporous silica coating. MSCs are labelled with gold nanoparticles (red signal in the right image) and are administered in vivo in order to determine the distribution of MSCs based on the gold core of the nanoparticles and their fluorescent coating," says Lotte. Read more about Lotte's work on our website ➡️ https://lnkd.in/eY_rkX4c #premstem #h2020 #research #nanoparticles #stemcells #preterm #celltherapies #neuroscience #phdlife #phd MERLN Institute for Technology-Inspired Regenerative Medicine | Maastricht UMC+

To end Brain Awareness Week, why not take a look at our 'Why is the brain vulnerable' playlist on the PREMSTEM YouTube channel? In these short videos you'll learn some quick facts about nine different types of cell found in the brain, including oligodendrocytes, interneurons, astrocytes, microglia, neural stem cells, and purkinje cells. ➡️ https://lnkd.in/eFCnpNgj #premstem #h2020 #researcher #brain #brainscience #neuroscience #cells #youtube #BrainWeek #BrainAwarenessWeek Dana Foundation

For Brain Awareness Week we're sharing the latest research highlights of one of our scientific publications. We create these summaries for people who would like to learn about our research without reading the full paper. 'Umbilical cord-mesenchymal stem cells induce a memory phenotype in CD4+ T cells' was co-authored by PREMSTEM researchers Ezgi Sengun, Tim Wolfs, Valéry van Bruggen, Daan Ophelders, Irma Joosten and Renate van der Molen. The goal of the study was to create a cell culture model to observe the long-term effects of human mesenchymal stem cells (H-MSCs) on activated T cells. The aim was to better understand how H-MSCs can influence the immune system and help manage inflammation, especially in vulnerable populations like preterm babies. The results suggest that stem cells from umbilical cord tissue or blood could help to control inflammation and immune responses, possibly offering a way to improve the body’s healing processes. Read the research highlights on our website ➡️ https://lnkd.in/eZf44AS7 A special thanks to Ezgi and Daan for producing this summary of the paper, and to Hannah Raymond and Alishia Ballintine for their review and feedback! #premstem #h2020 #neuroscience #research #stemcells #brain #brainscience #researchpaper #laysummary #publication #BrainAwarenessWeek #BrainWeek | Dana Foundation | Maastricht University | Maastricht UMC+ | Radboudumc

PREMSTEM researchers are investigating stem cells donated from umbilical cord tissue and their potential to treat brain injury associated with preterm birth. For Brain Awareness Week, head to our resources page to read the fact sheet on this topic, available in various languages. ➡️ https://lnkd.in/dHcT8VD #premstem #h2020 #research #preterm #brain #neuroscience #stemcells #factsheet #BrainAwarenessWeek #BrainWeek Dana Foundation