Toronto Research Chemicals

Next week, we'll be exhibiting at Korea Lab 🇰🇷. Stop by booth 7L411 in Hall 7 and say hi to our APAC Channel Manager, Yongjae Joo! We can't wait to connect with industry professionals in Asia and showcase our widest range of research chemicals for medicinal R&D and high quality reference standards for pharmaceutical quality control. Discover more at https://ow.ly/3WLG50VyQWR #KoreaLab #pharma #LifeScience #QualityControl #ScienceForaSaferWorld

From discovery to delivery– your trusted partner in pharmaceutical development. Explore the latest LGC Pharmaceutical Services brochure at https://ow.ly/IFQq50VyQpl Bringing a drug to market is never easy — every stage presents its own unique challenges. With over 40 years of experience in complex organic synthesis, LGC is trusted by leading pharmaceutical companies to provide the critical support needed across research, development, and manufacturing. Our new interactive brochure highlights how we help accelerate development and minimise risk through: ✅ Custom synthesis – from stable isotope-labelled compounds to novel scaffolds ✅ Bulk supply – tailored quantities of APIs, metabolites, and impurities ✅ Reference standards – produced to your exact specifications ✅ Pharmacokinetic and biomarker support – built on deep SIL expertise ✅ Inventory and batch management – ensuring supply continuity and flexibility With newly expanded R&D facilities in Toronto, GMP capabilities in Luckenwalde, and a team of 100+ PhD and MSc scientists, we’re equipped to support your evolving needs — from candidate optimisation to batch release. #DrugDiscovery #CustomSynthesis #Bioanalysis #DrugSafety #Pharmacokinetics

Save the Date! 📅April 24, 2025 – The SelectScience® webinar is coming soon! Register now: https://ow.ly/aTR950VyQ5r Want to learn more about how to optimise your PFAS analysis? Join this free webinar and hear from our LGC Standards experts Dr Dan Biggerstaff nd Dr Kelly Cheshire discuss how to maintain data integrity with analytes in various methods including the EPA Method 1633, UCMR 5 and EU DWD. In this insightful webinar, you will also learn how to: 🔬 Discover PFAS reference materials that are quality accredited to keep pace with fast-changing regulations. 🔬 Enhance efficiency in your environmental and food and beverage analytical testing facilities. #PFASMonitoring #EPARegulations #EnvironmentalTesting #AnalyticalChemistry #ScienceForaSaferWorld

World Parkinson’s Day: The Growing Crisis of an Aging Population On World Parkinson’s Day, we recognise the urgent need for innovative approaches to address one of the fastest-growing neurological disorders. Today, more than 10 million people worldwide live with Parkinson’s disease, and as life expectancy increases, the number of cases is expected to double in the coming decades. For years, treatments such as levodopa and MAO-B inhibitors have helped manage symptoms, but they do not slow the progression of the disease. The race is on for next-generation therapies that target the root causes—neuroinflammation, oxidative stress, protein misfolding, and neuronal loss. 🔬At TRC, we support Parkinson’s drug discovery with hundreds of compounds- referenced in over 1,000 research publications. Our LGC Mikromol™ range provides high-quality active APIs and impurity reference materials, including Apomorphine Hydrochloride Hemihydrate, ensuring the reliable manufacturing of essential treatments for Parkinson’s disease. Discover more at https://ow.ly/VGcf50VyNFN With millions at risk and no cure available, the need for innovation has never been greater. #WorldParkinsonsDay #Neurology #DrugDiscovery #ParkinsonsResearch #Neuroinflammation #Neruroscience

Did you know Coca-Cola once contained cocaine? When pharmacist John Stith Pemberton created the drink in 1886, it was marketed as a medicinal tonic, containing coca leaf extract (which naturally contains cocaine) and kola nut for caffeine. 🔬 How much cocaine? Early formulas contained around 9 mg per serving—far lower than modern recreational doses but enough to have a stimulating effect. It was promoted as a “brain tonic” to boost energy and relieve fatigue. 🚫 When was cocaine removed? Due to growing concerns, Coca-Cola began using "spent" coca leaves (with the cocaine removed) in 1904. By 1929, the drink was completely cocaine-free. ⚖️ Still using coca leaves? Yes! Coca-Cola still uses a decocainised coca extract, legally processed by the Stepan Company in the US under DEA supervision. LGC Standards provide high-quality forensic and toxicology reference materials, including cocaine reference standards, formulated for forensic testing (https://ow.ly/N74050VvbHu) and medical research (https://ow.ly/E01r50VvbHv). 🗞️Read more about coca's history at https://ow.ly/Klqc50VvbHt #MoleculeMonday #PharmaceuticalChemistry #DrugDiscovery

Download our latest white paper to explore the latest advances in transporter science and modelling techniques now: https://lnkd.in/e46DDPft False positives in in vitro toxicology and drug-drug interaction (DDI) studies remain a major bottleneck in drug development, leading to unnecessary clinical trials, inflated costs and delayed access to life saving therapies. However, recent advances in transporter science - including validation of biomarkers like coproporphyrin I (CPI) and next generation in vitro models such as organ on a chip, combined with modelling techniques - are transforming the landscape, enabling more accurate prediction of toxicity and DDI scenarios This whitepaper provides practical guidance for drug developers on integrating biomarker and assay data to improve predictive reliability, in alignment with ICH M12 regulatory guidelines. #Whitepaper #DrugDevelopment #TransporterScience #InVitroToxicology #Biomarkers #PharmaceuticalResearch

We are pleased to announce the release of our new guide: Characterising Impurity Standards: What Defines “Good Enough?” https://ow.ly/k68J50VwtrW. Impurity reference standards (IRSs) are essential for identifying and quantifying impurities in pharmaceutical development and manufacturing accurately. However, due to the limited regulatory guidance on how much characterisation is truly needed for various applications, selecting the right standard can be challenging. To assist with this process, LGC Standards has created an interactive multimedia guide that is packed with expert insights to facilitate informed decision-making and ensure confidence in choosing the most suitable IRS for your specific needs. #ImpurityStandards #AnalyticalChemistry #PharmaIndustry #QualityControl

Did you know Coca-Cola once contained cocaine? When pharmacist John Stith Pemberton created the drink in 1886, it was marketed as a medicinal tonic, containing coca leaf extract (which naturally contains cocaine) and kola nut for caffeine. 🔬 How much cocaine? Early formulas contained around 9 mg per serving—far lower than modern recreational doses but enough to have a stimulating effect. It was promoted as a “brain tonic” to boost energy and relieve fatigue. 🚫 When was cocaine removed? Due to growing concerns, Coca-Cola began using "spent" coca leaves (with the cocaine removed) in 1904. By 1929, the drink was completely cocaine-free. ⚖️ Still using coca leaves? Yes! Coca-Cola still uses a decocainised coca extract, legally processed by the Stepan Company in the US under DEA supervision. LGC Standards provide high-quality forensic and toxicology reference materials, including cocaine reference standards, formulated for forensic testing (https://ow.ly/N74050VvbHu) and medical research (https://ow.ly/E01r50VvbHv). 🗞️Read more about coca's history at https://ow.ly/Klqc50VvbHt #MoleculeMonday #PharmaceuticalChemistry #DrugDiscovery

Epilepsy affects around 1% of people worldwide, yet available medications fail to control seizures in up to 30% of patients. There’s a critical need for innovation in drug design and therapeutic strategies. A recent study evaluated SSR504734, an investigational drug that selectively inhibits Glycine Transporter Type 1 (GlyT1)—previously explored in schizophrenia and anxiety—as a potential epilepsy treatment. Using our TRC research chemicals: GABA, GABA-D6 and SSR504734 metabolite, researchers precisely measured neurotransmitter changes, discovering that SSR504734: ✅ Made the brain more resistant to seizures ✅ Influenced inflammation markers linked to epilepsy ✅ Effectively reached therapeutic concentrations in the brain 🔬Learn more about our GABA-D6 product or read this research in the citation section here: https://ow.ly/4uIL50VtmfL Could targeting GlyT1 open a new path in epilepsy drug discovery? #EpilepsyResearch #DrugDiscovery #Neuroscience #GlyT1 #ProductCitation

If you have any PFAS monitoring-related questions, don't miss the opportunity to join us on April 24 for the SelectScience® webinar, 'PFAS reference material optimization to meet EPA regulatory compliance'. Register now: https://ow.ly/bPQ450Vtbuh. With tight regulations enforced by the EPA to keep drinking water safe, it is vital that we have accurate methods to quantify PFAS. In this free webinar, our LGC experts Dr. Dan Biggerstaff and Dr. Kelly Cheshire will discuss how to maintain data integrity with analytes in various methods including the EPA Method 1633, UCMR 5, and EU DWD. You can also learn how to: 🔬 Discover PFAS reference materials that are quality accredited to keep pace with fast-changing regulations 🔬 Improve efficiency in your environmental and food and beverage analytical testing facilities. #PFASMonitoring #EPARegulations #EnvironmentalTesting #AnalyticalChemistry #ScienceForaSaferWorld